Results 141 to 150 of about 1,849,669 (310)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Representing Symmetric Rank Two Updates [PDF]
Various quasi-Newton methods periodically add a symmetric "correction" matrix of rank at most 2 to a matrix approximating some quantity A of interest (such as the Hessian of an objective function).
David M. Gay
core
Rank Intersectionality and Othello
As a crucial concept in critical theory, intersectionality satisfies a need within global Shakespeare reception studies. The reason for this is the way it permits cross-currents between conceptions of race and gender in particular; it also allows for an ...
Paul Innes
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Design of high-efficiency low-complexity detection schemes for ultrawide bandwidth (UWB) systems is highly challenging. This contribution proposes a reduced-rank adaptive multiuser detection (MUD) scheme operated in least bit-errorrate (LBER) principles ...
Ahmed, Qasim +5 more
core +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Linear Transducers Simplify Roll Grinding
B. S. Pearn
doaj +1 more source
The uniqueness of expression for generalized quadratic matrices
It is shown that the expression as A2=αA+βP{A}^{2}=\alpha A+\beta P for generalized quadratic matrices is not unique by numerical examples. Then it is proven that the uniqueness of expression for generalized quadratic matrices is concerned not only with ...
Chen Meixiang +2 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source

