Results 191 to 200 of about 3,763,729 (331)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Antioxidant Clove Extract Inhibits Lipid Droplet Accumulation and Lipid Oxidation in Hepatocytes. [PDF]
Monde S, Dibwe DF, Iwasaki S, Hui SP.
europepmc +1 more source
Identifying Subspace Gene Clusters from Microarray Data Using Low-Rank Representation
Yan Cui, Chun-Hou Zheng, Jian Yang
openalex +2 more sources
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Correlations Between Carbon Structure and Properties by XRD and Raman Structural Studies During Coke Formation in Various Rank Coals. [PDF]
Tian L, Dou J, Chen X, Yu J.
europepmc +1 more source
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Reconstructing Spatial Localization Error Maps via Physics-Informed Tensor Completion for Passive Sensor Systems. [PDF]
Zhang Z, Huang Z, Wang C, Jiang Q.
europepmc +1 more source

