Results 201 to 210 of about 3,522,972 (323)
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Evaluation of data driven low-rank matrix factorization for accelerated solutions of the Vlasov equation. [PDF]
Jonnalagadda B, Becker S.
europepmc +1 more source
1-forms with the exterior derivative of maximal rank [PDF]
Tadashi Nagano
openalex +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Estimating the Number of Latent Ranks of the Fugl-Meyer Assessment Score for the Affected Upper Extremity After Stroke. [PDF]
Hara K+3 more
europepmc +1 more source
The decomposability of torsion free modules of finite rank [PDF]
Eben Matlis
openalex +1 more source
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Neural oscillation in low-rank SNNs: bridging network dynamics and cognitive function. [PDF]
Li B+5 more
europepmc +1 more source