Results 221 to 230 of about 3,725,370 (324)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Concerns of first-year medical students regarding their future profession: an international study. [PDF]

BMC Med Educ
Neumaier V, Bratu J, van Wijngaarden J, Ruiz M, Constantinou C, Lundman P, Wahlgren A, Kantenwein V, Berberat PO, Wijnen-Meijer M.   +9 more
europepmc   +1 more source

Ranked Choice Voting in Alameda County : A Natural Experiment

, 2020
Bo Hellekant
openalex   +1 more source

The shift-homological spectrum and parametrising kernels of rank functions [PDF]

Isaac Bird, Jordan Williamson, Alexandra Zvonareva   +2 more
openalex   +1 more source

THE-Ranking

, 2021
openaire   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

The F score ranks diagnostic tests and prediction models inconsistently with their clinical utility. [PDF]

Diagn Progn Res
Assel M, Vickers A.
europepmc   +1 more source

Symmetric Rank-One Quasi-Newton Methods for Deep Learning Using Cubic Regularization [PDF]

Aditya Ranganath, Mukesh Singhal, Roummel F. Marcia   +2 more
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

A drug-repurposing screen of FDA- and EMA-approved drugs identifies two NF-κB inhibitors active against eumycetoma. [PDF]

J Antimicrob Chemother
Ma J, van Doodewaerd BR, Biersack B, Verbon A, Geurink PP, van de Sande WWJ.   +5 more
europepmc   +1 more source