Accurate and efficient P-values for rank-based independence tests with clustered data using a saddlepoint approximation. [PDF]
Newer HA.
europepmc +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Denosumab attenuates knee osteoarthritis progression by inhibiting synovial inflammation via the RANK/TRAF6/FSTL1 signalling. [PDF]
Hu Y +16 more
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Structure-guided design of antibody CDRs to reduce their reactivity to treatment-emergent anti-drug antibodies. [PDF]
Johansson MU +13 more
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Secrecy Rate Maximization for Movable Antenna-Aided STAR-RIS in Integrated Sensing and Communication Systems. [PDF]
Chen G +6 more
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Th17-like cells and immunosuppressive macrophages infiltrate tertiary lymphoid structures with distinct maturation status in soft-tissue sarcoma. [PDF]
Petroni G +15 more
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Bearing Fault Diagnosis via FMD with Parameters Optimized by an Improved Crested Porcupine Optimizer. [PDF]
Pan P, Liu H, Lei B, Tang X.
europepmc +1 more source

