Results 251 to 260 of about 3,725,370 (324)

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Denosumab attenuates knee osteoarthritis progression by inhibiting synovial inflammation via the RANK/TRAF6/FSTL1 signalling. [PDF]

open access: yesNat Commun
Hu Y   +16 more
europepmc   +1 more source

Structure-guided design of antibody CDRs to reduce their reactivity to treatment-emergent anti-drug antibodies. [PDF]

open access: yesMAbs
Johansson MU   +13 more
europepmc   +1 more source

The ranking of scientists

open access: yesJournal of Biomedical Informatics, 2018
openaire   +2 more sources

Th17-like cells and immunosuppressive macrophages infiltrate tertiary lymphoid structures with distinct maturation status in soft-tissue sarcoma. [PDF]

open access: yesCell Death Dis
Petroni G   +15 more
europepmc   +1 more source

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