Results 121 to 130 of about 450,197 (278)
K-theory and homotopies of 2-cocycles on higher-rank graphs [PDF]
, 2015 Elizabeth Gillaspy
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RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer
Advanced Biology, EarlyView.Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav +5 more
wiley +1 more source
Dimension, depth and zero-divisors of the algebra of basic k-covers of a graph
Le Matematiche, 2008 We study the basic k-covers of a bipartite graph G; the algebra A(G) they span, first studied by Herzog, is the fiber cone of the Alexander dual of the edge ideal.
Bruno Benedetti +2 more
doaj
Structure theory and stable rank for C*-algebras of finite higher-rank graphs
, 2020 David Pask, Adam Sierakowski, Aidan Sims
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Advanced Biology, EarlyView.The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li +10 more
wiley +1 more source
Higher rank graphs from cube complexes and their spectral theory [PDF]
, 2021 Nadia S. Larsen, Alina Vdovina
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Advanced Biology, EarlyView.This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen +4 more
wiley +1 more source
Advanced Biology, EarlyView.The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran +5 more
wiley +1 more source
A Note on Brill–Noether Theory and Rank-Determining Sets for Metric Graphs [PDF]
, 2012 Chang Mou Lim +2 more
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Advanced Biology, EarlyView.A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso +5 more
wiley +1 more source