Results 121 to 130 of about 1,245,381 (307)

Phase 1, First‐In‐Human, Single‐/Multiple‐Ascending Dose Study of Iluzanebart in Healthy Volunteers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of iluzanebart, a fully human monoclonal antibody TREM2 (triggering receptor expressed on myeloid cells 2) agonist, after single‐ (SAD) and multiple‐ascending‐dose (MAD) administration.
Andreas Meier, Spyros Papapetropoulos, Andrew Marsh, Kelly Neelon, David Stiles, Ryan O'Mara, Evan A. Thackaberry, Marco Colonna, Raj Rajagovindan   +8 more
wiley   +1 more source

Inference of Curvilinear Structure based on Learning a Ranking Function and Graph Theory

, 2015
To detect curvilinear structures in natural images, we propose a novel rankinglearning system and an abstract curvilinear shape inference algorithm based on graph theory. Weanalyze the curvilinear structures as a set of small line segments. In this work, the rankings ofthe line segments are exploited to systematize the topological feature of the ...
Jeong, Seong-Gyun, Tarabalka, Yuliya, Nisse, Nicolas, Zerubia, Josiane   +3 more
openaire   +4 more sources

Combination Therapy With Vigabatrin and Prednisolone Versus Vigabatrin Alone for Infantile Spasms

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The study evaluated the effectiveness of combination therapy with vigabatrin and prednisolone versus vigabatrin alone for treating infantile epileptic spasms syndrome (IESS). Methods This single‐center, single‐blind, randomized trial enrolled infants aged 2–14 months with new‐onset IESS, randomly assigned them (1:1) to receive either
Rachata Boonkrongsak, Kantapon Trongkamolchai, Sirorat Suwannachote, Somjit Sri‐Udomkajorn, Raviwan Wittawassamrankul, Ravindra Arya, Kullasate Sakpichaisakul   +6 more
wiley   +1 more source

A Probabilistic Interpretation of Sampling Theory of Graph Signals

, 2015
We give a probabilistic interpretation of sampling theory of graph signals. To do this, we first define a generative model for the data using a pairwise Gaussian random field (GRF) which depends on the graph.
Gadde, Akshay, Ortega, Antonio
core   +1 more source

The method of judging satisfactory consistency of linguistic judgment matrix based on adjacency matrix and 3-loop matrix

AIMS Mathematics
Language phrases are an effective way to express uncertain pieces of information, and easily conforms to the language habits of decision makers to describe the evaluation of things. The consistency judgment of a linguistic judgment matrices is the key to
Fengxia Jin, Feng Wang, Kun Zhao, Huatao Chen, Juan L.G. Guirao   +4 more
doaj   +1 more source

Universal Proteomic Signature After Exercise‐Induced Muscle Injury in Muscular Dystrophies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Several neuromuscular disorders (NMDs) are characterized by progressive muscle damage and are marked by the elevation of circulating muscle proteins from activity‐related injury. Despite a diverse array of genetic drivers, many NMDs share similar patterns of exercise intolerance and higher concentrations of muscle injury proteins ...
Mads G. Stemmerik, Benjamin Barthel, Nanna R. Andersen, Sofie V. Skriver, Alan J. Russell, John Vissing   +5 more
wiley   +1 more source

The Maximum Order of Reduced Square(0, 1)-Matrices with a Given Rank [PDF]

We look for the maximum order of a square (0, 1)-matrix A with a fixed rank r, provided A has no repeated rows or columns. If A is the adjacency matrix of a graph, Kotlov and Lovász [J. Graph Theory 23, 1996] proved that the maximum order equals Θ(2r/2).
Haemers, W.H., Peeters, M.J.P.
core   +1 more source

An algebraic analysis of the graph modularity

, 2014
One of the most relevant tasks in network analysis is the detection of community structures, or clustering. Most popular techniques for community detection are based on the maximization of a quality function called modularity, which in turn is based upon
Fasino, Dario, Tudisco, Francesco
core   +1 more source

Management and Outcomes in Confirmed or Suspected Acute Symptomatic Seizure: Role of Structured Outpatient Care

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Post‐discharge management and outcomes of acute symptomatic seizures (ASyS) remain underexplored. We analyzed post‐discharge ASM management and outcomes in ASyS patients undergoing continuous EEG (cEEG), including the role of outpatient care through a post‐acute symptomatic seizure (PASS) clinic. Methods We performed a single‐center,
Vineet Punia, MarieElena Byrnes, Nicolas R. Thompson, Neishay Ayub, Clio Rubinos, Sahar Zafar, Adithya Sivaraju, Zhong Ying, Jessica R. Fesler, Stephen Hantus, Post‐Acute Symptomatic Seizure Investigation and Outcomes Network (PASSION) investigators   +10 more
wiley   +1 more source

The Relationship Between the Distinguishing Number and the Distinguishing Index with the Detection Number

پژوهش‌های ریاضی, 2020
Introduction The graph is a mathematical model for a discrete set whose members are interlinked in some way. The members of this collection can be the different parts of the earth and the connections between them are bridges that tie them together (like ...
Saeid Alikhani, Samaneh Soltani
doaj