Results 221 to 230 of about 13,396 (303)

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Advancing the frontier of rare disease modeling: a critical appraisal of in silico technologies. [PDF]

NPJ Digit Med
Pistollato F, Furtmann F, Marshall LJ, Parvatam S, Turner J, Musuamba FT, Russo G, Pappalardo F.   +7 more
europepmc   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Purification, identification, and <i>in silico</i> screening of a multifunctional octapeptide from <i>semen armeniacae</i> glutelin-2 hydrolysates: restraining mechanisms to Keap1 and ACE, stability, and ferrous-transport efficiency. [PDF]

Front Nutr
Jin Z, Dang L, Li Y, Feng C, Song X, Wei Z, Liu J, Wang H, Zhang Y.   +8 more
europepmc   +1 more source

Academic Performance Based on Gender using Filter Ranker Algorithms - An Experimental Analysis in Sultanate of Oman

, 2019
Reshmy Krishnan, Hameetha Beegum, Sadiq Hussain, A Aziz, N Ismail, & Ahmad, Amjad Saa, Abu, S Bradley, J Taylor, F Ahmad, N Ismail, A Abdulaziz, R Sumitha, E Vinothkumar, Maryam Zaffar, M Doshi, W Punlumjeak, N Rachburee, Asha Karegowda, A Gowda, M Manjunath, Jayaram   +22 more
openalex   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

Enzymatic Hydrolysis of Porcine Blood as a Strategy to Obtain a Peptide-Rich Functional Ingredient. [PDF]

Int J Mol Sci
Moreno-Mariscal C, Moroni F, Pérez-Sánchez J, Mora L, Toldrá F.   +4 more
europepmc   +1 more source

Do Large Language Models Rank Fairly? An Empirical Study on the Fairness of LLMs as Rankers [PDF]

Yuan Wang, Xuyang Wu, Hsin-Tai Wu, Zhiqiang Tao, Yifang Ma   +4 more
openalex   +1 more source

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller, Lauren N. Coffey, Shelley R. H. Mockler, Katie M. Laubscher, Carrie M. Stephan, M. Bridget Zimmerman, Katherine D. Mathews   +6 more
wiley   +1 more source

Rational Design of PCR12mod6, a Cathelicidin-HR-Derived Peptide with Enhanced Dual-Action Antimicrobial and Antioxidant Activity. [PDF]

ACS Omega
Tankrathok A, Karnmongkol C, Kamlaiwong P, Srisamoot N, Wiriyaampaiwong P, Jangpromma N.   +5 more
europepmc   +1 more source