Results 1 to 10 of about 505,251 (319)

Model parameters of technical and tactical actions in the competitive activities of volleyball players

open access: yesPhysical Education of Students, 2013
The application of modeling of technical and tactical actions as one of the leading components of the control system of competitive activities of highly skilled volleyball players. It is show that the proposed modeling techniques can generate the optimum
E.Iu. Doroshenko
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Sync-Rank: Robust Ranking, Constrained Ranking and Rank Aggregation via Eigenvector and SDP Synchronization [PDF]

open access: yesIEEE Transactions on Network Science and Engineering, 2016
We consider the classical problem of establishing a statistical ranking of a set of $n$ items given a set of inconsistent and incomplete pairwise comparisons between such items. Instantiations of this problem occur in numerous applications in data analysis (e.g., ranking teams in sports data), computer vision, and machine learning.
openaire   +2 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

APPLICATION OF PROMETHEE II METHOD IN DECISION-MAKING FOR GRANT DISTRIBUTION IN ACADEMIC ENVIRONMENT [PDF]

open access: yesProceedings on Engineering Sciences
The PROMETHEE II algorithm is used for multi-criteria analysis in decision-making. This algorithm compares and ranks various choices based on pre-determined criteria.
Raja Ayu Mahessya , Novi Trisna
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Zanieczyszczenia środowiska a działalność proekologiczna w Polsce w 2015 roku w świetle wielowymiarowej analizy porównawczej

open access: yesZeszyty Naukowe Szkoły Głównej Gospodarstwa Wiejskiego w Warszawie. Problemy Rolnictwa Światowego, 2017
Rozwój cywilizacyjny niesie z sobą postępujący proces degradacji środowiska. Aby zapobiec ewentualnie ograniczyć skutki tego procesu, podejmuje się działania proekologiczne.
Karol Kukuła
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

University Ranking, an Important Quality-Assurance Tool

open access: yesEIRP Proceedings, 2012
“University Rankings” - or “League Tables”, as they are known in the United Kingdom – have in ashort period of time become an important feature in policy-making and practice in higher education.
Crina Rădulescu
doaj  

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