Results 91 to 100 of about 1,776,095 (267)

Comparison and ranking of superelasticity of different austenite active nickel-titanium orthodontic archwires using mechanical tensile testing and correlating with its electrical resistivity

Journal of Pharmacy and Bioallied Sciences, 2016
Introduction: The application of light and continuous forces for optimum physiological response and the least damage to the tooth supporting structures should be the primary aim of an orthodontist.
D Nagarajan, Balashanmugam Baskaranarayanan, K Usha, M S Jayanthi, M Vijjaykanth   +4 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Ranking Tourism Attractions According to their Suitability for Public Investment in Gansu Province, China

Téoros, 2008
While assessments of tourism attractions are among the fundamentals of tourism planning, they are the “poor cousins” of accessibility, transportation, and accommodations analysis (Pearce, 1991).
Nick Novakowski, Rémy Tremblay, Edward Leman   +2 more
doaj  

COGNITIVE MODELING AS A METHOD OF QUALITATIVE ANALYSIS OF IT PROJECTS

Вісник Національного технічного університету «ХПÌ». Серія: Стратегічне управління, управління портфелями, програмами та проектами, 2016
The example project implementing automated CRM-system demonstrated the possibility and features of cognitive modeling in the qualitative analysis of project risks to determine their additional features.
Інна Ігорівна ОНИЩЕНКО
doaj   +1 more source

Ranking the rankings

, 2014
In een academische wereld die steeds competitiever wordt, willen we graag weten wat ‘de beste’ universiteit is. Verschillende rankings bedienen ons op onze wenken, waaronder Times Higher Education, Sjanghai, QS en Leiden. De kritiek op die lijsten is echter niet mals, ook omdat universiteiten graag selectief shoppen in de resultaten.
Sikkema, A., van Ruitenbeek, H.C.G., Gerritsma, W., Wouters, P.   +3 more
openaire   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Modeling and Evaluation of Innovative Activities in The Banking Services Sector

Online Academic Journal of Information Technology, 2018
A new method for research the innovation processes in the service sector is suggested to provide a quantitative basis for measuring various aspects of innovation and to investigate a number of factors that may affect innovation in the banking services ...
Özdemir Yahya, A.f. Huseynov
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

The Power-weakness Ratios (PWR) as a Journal Indicator: Testing the “Tournaments” Metaphor in Citation Impact Studies

Journal of Data and Information Science, 2017
Ramanujacharyulu developed the Power-weakness Ratio (PWR) for scoring tournaments. The PWR algorithm has been advocated (and used) for measuring the impact of journals. We show how such a newly proposed indicator can empirically be tested.
Leydesdorff Loet, de Nooy Wouter, Bornmann Lutz   +2 more
doaj   +1 more source

Visibilidad e impacto de la producción científica de la Facultad de Ingeniería Industrial de la Cujae de Cuba (2003-2012)

Investigación Bibliotecológica: Archivonomía, Bibliotecología e Información, 2017
Los estudios bibliométricos aplicados a la producción científica de las universidades aportan información valiosa para la toma de decisiones en materia de planificación y evaluación de sus actividades de investigación.
María Sonia Fleitas Triana, Claudia Hernández Oquendo, Sandra Guerra Castillo   +2 more
doaj   +1 more source