Results 121 to 130 of about 606,719 (306)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Top ranking economics journals impact variability and a ranking update to the year 2002 [PDF]

open access: yes
In this paper I address four questions concerning the quality of scientific economic papers. First, I validate the ex-ante procedure of computing the average impact of economic papers by comparing its results with the expost values.
Pedro C. Vieira
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

University Ranking, an Important Quality-Assurance Tool

open access: yesEIRP Proceedings, 2012
“University Rankings” - or “League Tables”, as they are known in the United Kingdom – have in ashort period of time become an important feature in policy-making and practice in higher education.
Crina Rădulescu
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

La industria publicitaria iberoamericana caracterizada desde un metaestudio de los anuncios premiados en festivales

open access: yesPalabra Clave, 2018
En este artículo, los festivales y premios de publicidad son el objeto de estudio para caracterizar la publicidad, con un doble objetivo: por un lado, validar el uso de la información registrada en los festivales de publicidad internacionales, anuncios y
Rafael Repiso   +4 more
doaj  

Ranking Learning-to-Rank Methods.

open access: yes, 2017
We present a cross-benchmark comparison of learning-to-rank methods using two evaluation measures: the Normalized Winning Number and the Ideal Winning Number. Evaluation results of 87 learning-to-rank methods on 20 datasets show that ListNet, SmoothRank, FenchelRank, FSMRank, LRUF and LARF are Pareto optimal learning-to-rank methods, listed in ...
Hiemstra, D., Tax, N., Bockting, S.
openaire   +2 more sources

On rank correlation and the distance between rankings [PDF]

open access: yesProceedings of the 32nd international ACM SIGIR conference on Research and development in information retrieval, 2009
Rank correlation statistics are useful for determining whether a there is a correspondence between two measurements, particularly when the measures themselves are of less interest than their relative ordering. Kendall's - in particular has found use in Information Retrieval as a "meta-evaluation" measure: it has been used to compare evaluation measures,
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Ranking the ‘Diamond Core’ economic journals: A note [PDF]

open access: yes
By estimating the production frontier with the application of Data Envelopment Analysis (DEA) we rank the ‘Diamond Core’ economic journals as has been presented by Diamond (1989).
Halkos, George, Tzeremes, Nickolaos
core  

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