Results 101 to 110 of about 372,511 (339)

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla   +15 more
wiley   +1 more source

A Point-Set-Based Footprint Model and Spatial Ranking Method for Geographic Information Retrieval

open access: yesISPRS International Journal of Geo-Information, 2016
In the recent big data era, massive spatial related data are continuously generated and scrambled from various sources. Acquiring accurate geographic information is also urgently demanded.
Yong Gao   +3 more
doaj   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

Exploring the Importance of Entities in Semantic Ranking

open access: yesInformation, 2019
In recent years, entity-based ranking models have led to exciting breakthroughs in the research of information retrieval. Compared with traditional retrieval models, entity-based representation enables a better understanding of queries and documents ...
Zhenyang Li   +5 more
doaj   +1 more source

Design Patterns for Fusion-Based Object Retrieval

open access: yes, 2017
We address the task of ranking objects (such as people, blogs, or verticals) that, unlike documents, do not have direct term-based representations. To be able to match them against keyword queries, evidence needs to be amassed from documents that are ...
C Macdonald   +3 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Cluster-based information retrieval using pattern mining

open access: yesApplied intelligence (Boston), 2020
This paper addresses the problem of responding to user queries by fetching the most relevant object from a clustered set of objects. It addresses the common drawbacks of cluster-based approaches and targets fast, high-quality information retrieval.
Y. Djenouri   +3 more
semanticscholar   +1 more source

Ranking of Search Requests in the Digital Information Retrieval System Based on Dynamic Neural Networks

open access: yesComplexity, 2022
The article is devoted to the problem of optimization of search request ranking algorithms in the digital information retrieval system. The algorithm of functioning of the neural network ranking unit based on Hopfield neural network is built. The ability
Viera Bartosova   +4 more
doaj   +1 more source

The State-of-the-arts in Focused Search [PDF]

open access: yes, 2009
The continuous influx of various text data on the Web requires search engines to improve their retrieval abilities for more specific information. The need for relevant results to a user’s topic of interest has gone beyond search for domain or type ...
Li, Rongmei
core   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

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