Results 81 to 90 of about 142,624 (305)

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Ranking-based Deep Cross-modal Hashing

open access: yes, 2019
Cross-modal hashing has been receiving increasing interests for its low storage cost and fast query speed in multi-modal data retrievals. However, most existing hashing methods are based on hand-crafted or raw level features of objects, which may not be ...
Domeniconi, Carlotta   +5 more
core   +1 more source

Examining assessor attributes at HARD 2005 [PDF]

open access: yes, 2006
The TREC HARD (High accuracy Retrieval from Documents) track was motivated to investigate techniques for personalised retrieval of documents. Through the use of a limited dialogue with the TREC assessors, the track facilitated the gathering and ...
Baillie, Mark, Ruthven, Ian
core   +1 more source

Exploring the Importance of Entities in Semantic Ranking

open access: yesInformation, 2019
In recent years, entity-based ranking models have led to exciting breakthroughs in the research of information retrieval. Compared with traditional retrieval models, entity-based representation enables a better understanding of queries and documents ...
Zhenyang Li   +5 more
doaj   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

The State-of-the-arts in Focused Search [PDF]

open access: yes, 2009
The continuous influx of various text data on the Web requires search engines to improve their retrieval abilities for more specific information. The need for relevant results to a user’s topic of interest has gone beyond search for domain or type ...
Li, Rongmei
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Enhancing Medical Image Retrieval with UMLS-Integrated CNN-Based Text Indexing

open access: yesDiagnostics
In recent years, Convolutional Neural Network (CNN) models have demonstrated notable advancements in various domains such as image classification and Natural Language Processing (NLP).
Karim Gasmi, Hajer Ayadi, Mouna Torjmen
doaj   +1 more source

Relevant Feedback Based Accurate and Intelligent Retrieval on Capturing User Intention for Personalized Websites

open access: yesIEEE Access, 2018
With the rapid growth of networking, cyber-physical-social systems (CPSSs) provide vast amounts of information. Aimed at the huge and complex data provided by networking, obtaining valuable information to meet precise search needs when capturing user ...
Yayuan Tang   +4 more
doaj   +1 more source

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