Results 81 to 90 of about 152,300 (264)

Implementation of a Cohort Retrieval System for Clinical Data Repositories Using the Observational Medical Outcomes Partnership Common Data Model: Proof-of-Concept System Validation

JMIR Medical Informatics, 2020
BackgroundWidespread adoption of electronic health records has enabled the secondary use of electronic health record data for clinical research and health care delivery.
Liu, Sijia, Wang, Yanshan, Wen, Andrew, Wang, Liwei, Hong, Na, Shen, Feichen, Bedrick, Steven, Hersh, William, Liu, Hongfang   +8 more
doaj   +1 more source

Efficient AUC Optimization for Information Ranking Applications

, 2016
Adequate evaluation of an information retrieval system to estimate future performance is a crucial task. Area under the ROC curve (AUC) is widely used to evaluate the generalization of a retrieval system. However, the objective function optimized in many
C Cortes, C Manning, CJ Burges, Q Wu, T Calders, T Fawcett, T Qin   +6 more
core   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

The Performance of Boolean Retrieval and Vector Space Model in Textual Information Retrieval

CommIT Journal, 2017
Boolean Retrieval (BR) and Vector Space Model (VSM) are very popular methods in information retrieval for creating an inverted index and querying terms.
Budi Yulianto, Widodo Budiharto, Iman Herwidiana Kartowisastro   +2 more
doaj   +1 more source

RankEval: Evaluation and investigation of ranking models

SoftwareX, 2020
RankEval is a Python open-source tool for the analysis and evaluation of ranking models based on ensembles of decision trees. Learning-to-Rank (LtR) approaches that generate tree-ensembles are considered the most effective solution for difficult ranking ...
Claudio Lucchese, Cristina Ioana Muntean, Franco Maria Nardini, Raffaele Perego, Salvatore Trani   +4 more
doaj   +1 more source

Learning a Deep Listwise Context Model for Ranking Refinement

, 2018
Learning to rank has been intensively studied and widely applied in information retrieval. Typically, a global ranking function is learned from a set of labeled data, which can achieve good performance on average but may be suboptimal for individual ...
Ai, Qingyao, Bi, Keping, Croft, W. Bruce, Guo, Jiafeng   +3 more
core   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

IDENTIFYING DOCUMENT-LEVEL TEXT PLAGIARISM: A TWO-PHASE APPROACH [PDF]

Journal of Engineering Science and Technology, 2017
The rapid evolution of information content and its ease of access have made the field of research and academia so vulnerable to plagiarism. Plagiarism is an act of intellectual theft and information breach which must be restricted to ensure educational ...
VANI K., DEEPA GUPTA
doaj  

Retractions in rheumatology: trends, causes, and implications for research integrity

Arthritis Care &Research, Accepted Article.
Objective We aimed to describe the trends and main reasons for study retraction in rheumatology literature. Methods We reviewed the Retraction Watch database to identify retracted articles in rheumatology. We recorded the main study characteristics, authors’ countries, reasons for retraction, time from publication to retraction, and trends over time ...
Anna Maria Vettori, Michele Iudici
wiley   +1 more source