Results 51 to 60 of about 68,272 (245)
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Information, 2012 In today’s economy, one of the most important national indicators of economic growth performance is the country’s ability to produce new technology—and use it responsibly and efficiently—for environmental ...
Edoardo Magnone
doaj +1 more source
SSRN Electronic Journal, 2011 Research rankings based on publications and citations today dominate governance of academia. Yet they have unintended side effects on individual scholars and academic institutions and can be counterproductive. They induce a substitution of the taste for science by a taste for publication.
Frey, Bruno S, Osterloh, Margit
openaire +3 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Journal of Data and Information Science, 2022 A key question when ranking universities is whether or not to allocate the publication output of affiliated hospitals to universities. This paper presents a method for classifying the varying degrees of interdependency between academic hospitals and ...
Elizondo Andrea Reyes +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Proposal of an objective formula-based model for equitable ranking of veterinary colleges
Frontiers in Veterinary ScienceIntroductionWe suggest an objective ranking formula that has wide national and international application. The new formula is presented with U.S. Colleges of Veterinary Medicine as an example.
Robert M. Gogal, Steven David Holladay
doaj +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Regional science research in the Nordic countries in the light of some chosen international journals
European Journal of Spatial Development, 2005 This article analyzes the evolution of research in regional science in the Nordic countries in the period 1991-2000, situating it in an international context.
Raul Ramos +2 more
doaj +1 more source