Results 91 to 100 of about 57,630 (294)
Increasing the Reliability of Simulation Tests in Navigation and Maneuvering Simulators Using the k-Epsilon Model Based on the RANS Method. [PDF]
Sensors (Basel), 2021 Czaplewski K, Swierczynski S, Zwolan P.
europepmc +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Review of multi-fidelity models
Multi-fidelity models provide a framework for integrating computational models of varying complexity, allowing for accurate predictions while optimizing computational resources.
Fernández-Godino, M. Giselle
core +1 more source
Degrees and distances in random and evolving Apollonian networks [PDF]
, 2013 This paper studies Random and Evolving Apollonian networks (RANs and EANs), in d dimension for any d>=2, i.e. dynamically evolving random d dimensional simplices looked as graphs inside an initial d-dimensional simplex.
Kolossváry, István +2 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Journal of Marine Science and Engineering, 2018 In the past several decades, many papers have been published on fluid–structure coupled calculations to analyse the hydro-elastic response of flexible (composite) propellers.
Pieter Maljaars +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Numerical investigation of air-entrainment in skimming flow over stepped spillways
Theoretical and Applied Mechanics Letters, 2016 As a widely used flood energy dissipator, the stepped spillway can significantly dissipate the kinetic or hydraulic energy due to the air-entrainment in skimming flow over the steps.
Jiemin Zhan, Jianbo Zhang, Yejun Gong
doaj +1 more source
Fronthaul-Constrained Cloud Radio Access Networks: Insights and Challenges
, 2015 As a promising paradigm for fifth generation (5G) wireless communication systems, cloud radio access networks (C-RANs) have been shown to reduce both capital and operating expenditures, as well as to provide high spectral efficiency (SE) and energy ...
Lau, V., Peng, M., Poor, H. V., Wang, C.
core +2 more sources
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source