Results 101 to 110 of about 512,570 (299)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Analisis Nilai Kepadatan dan CBR Pada Gradasi Batas Atas, Median, dan Bawah Berdasarkan Rumus Cooper [PDF]

, 2016
Highway is an infrastructure that is essential to people's lives, because it can affect the economy of a region. The problem of damage that occur each year and rising material prices pushing for road pavement recycling.
, Ir. Agus Riyanto MT., , Ir. Sri Sunarjono ST., MT., PhD., Mahmudi, Imam   +2 more
core  

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

The Association Between Radiation-Induced miR-208a, Cancer Recurrence and Death Risk in Patients with Non-Small Cell Lung Cancer

International Journal of General Medicine
Wenjing Ji, Yanzhi Bi, Qian Zheng, Ruirui Sun, Kejun Dai Oncology Department, Changzhou Cancer Hospital, Changzhou City, Jiangsu Province, 213000, People’s Republic of ChinaCorrespondence: Kejun Dai, Oncology Department, Changzhou Cancer Hospital, No. 68
Ji W, Bi Y, Zheng Q, Sun R, Dai K
doaj  

The performance evaluation of hedge funds: a comparison of different approaches using European data [PDF]

The standard approach to the evaluation of funds assumes a normal return distribution and uses the variance as a measure of the funds risk. A few characteristics of hedge funds, such as the remuneration mechanism of the portfolio manager, make this ...
Carretta, Alessandro, Mattarocci, Gianluca   +1 more
core   +1 more source

Persistent Bilateral [18F]THK5351 and Migrating Unilateral [18F]FDG Uptake in Anti‐LGI1 Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Anti–leucine‐rich glioma‐inactivated 1 encephalitis (LGI1‐E) can cause persistent cognitive deficits, but the mechanisms remain unclear. A 40‐year‐old woman with LGI1‐E presented with subacute cognitive deficits and showed mild left medial temporal lobe (MTL) swelling and fluid‐attenuated inversion recovery (FLAIR) hyperintensity on initial ...
Yusuke Akitomi, Kenichiro Taira, Masanori Kurihara, Kenji Ishibashi, Kenji Ishii, Fumio Suzuki, Aya Midori Tokumaru, Makoto Hara, Atsushi Iwata   +8 more
wiley   +1 more source

Innovate for Impact: Young Adults Education and Empowerment for Climate Action

Australian Journal of Environmental Education
Anthropogenic climate change is a significant driver of disasters, such as tropical storms, floods, drought and loss of biodiversity, amplifying their frequency and severity worldwide. The annual incidence of extreme weather-related events increases with
Shelley Rap, Moran Bodas
doaj   +1 more source

Effects of Causal Beliefs About Gout on Public Views About Gout Management: A Randomized Experimental Study

Arthritis Care &Research, EarlyView.
Objective Despite well‐described biologic causes, the public views unhealthy lifestyle choices as the primary cause of gout. This study investigated how causal beliefs about gout influence the public's views about its management. Methods In a randomized study, 201 members of the public viewed one of two 2‐minute videos about gout.
Rachel Murdoch, Borislav Mihov, Anne Horne, Keith J. Petrie, Gregory D. Gamble, Lachlan Fleck, Nicola Dalbeth   +6 more
wiley   +1 more source

The Hydraulic Mission and the Mexican Hydrocracy: Regulating and Reforming the Flows of Water and Power [PDF]

In Mexico, the hydraulic mission, the centralisation of water control, and the growth of the federal hydraulic bureaucracy (hydrocracy) recursively shaped and reinforced each other during the 20th century.
Rap, E.R., Vargas-Velázquez, S., Wester, P.   +2 more
core   +2 more sources

The referee assignment problem [PDF]

, 2019
In collaboration between a UPC spinoff, Barcelogic, and the Dutch Football Federation (KNVB), we define, study, implement and evaluate different approaches for solving the so-called Referee Assignment Problem(RAP).
Vallespi Soro, Farners
core