Results 51 to 60 of about 86,732 (284)
Experimental Investigation on Rheological Properties of Recycled Asphalt Pavement Mastics
Applied Rheology, 2015 Studies have shown that rheology of asphalt mastic plays an important role in pavement performance, specifically for the case of recycled asphalt pavement (RAP) mastics which contains mostly aged binder.
Mannan Umme Amina +3 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
HIGHER SCHOOL AND EMPLOYER ARE BUSINESS-EDUCATION PARTNERS
Модернизация, инновация, развитие, 2016 The competence approach in education means to focus on developing learning capabilities, self-determination, socialization and development of personality.
V. A. Pokhvoshchev +2 more
doaj
Linguistic and Extralinguistic Aspects of Study of Modern Russian Rap Texts
Научный диалог, 2021 An overview of modern domestic and foreign linguistic studies of rap texts is presented. The features of rap as part of the global hip-hop culture are considered.
E. V. Grudeva, A. A. Diveeva
doaj +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
DEVELOPMENT OF METHODS FOR STATE MANAGEMENT OF INVESTMENT PROCESSES, INVESTMENT OF RESOURCES
Модернизация, инновация, развитие, 2016 Owing to the accessibility to funds and resources required to support economics on the whole and most important branches in particular, the state is main investor to real sector of Russian economics. Unfortunately, this investment activity is implemented
A. Yu. Semenikhin
doaj
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Characterization of Recovered Bitumen from Coarse and Fine Reclaimed Asphalt Pavement Particles
Infrastructures, 2019 In the current era of road construction, it is common to add a small amount of reclaimed asphalt pavement (RAP) in asphalt mixes without significantly changing properties such as stiffness and low-temperature cracking resistance. Not only can these mixes
Saeed S. Saliani +3 more
doaj +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source