Results 81 to 90 of about 2,823,635 (315)

Private Sector Rapid Care Analysis Toolkit

A Private Sector Rapid Care Analysis toolkit (PS RCA) is a rapid process for businesses and workers to understand the heavy responsibility and long hours of unpaid care and domestic work (UCDW), usually done by women workers.
Kidder, Thalia, Pionettie, Carine
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Utilizing rapid qualitative assessment and thematic analysis methods to identify and share promising case investigation and contact tracing practices with people in refugee, immigrant, and migrant communities during COVID-19

Frontiers in Public Health
In the early months of the COVID-19 pandemic The National Resource Center for Refugees, Immigrants and Migrants (NRC-RIM) was established. NRC-RIM initially sought to rapidly identify promising case investigation and contact tracing (CICT) practices ...
Windy Fredkove, Erin Mann, Seja Abudiab, Diego De Acosta, Yesenia Garcia, Sarah J. Hoffman, Sayyeda Karim, Christine Thomas, Kimberly Kan-Yih Yu, Katherine Yun, Elizabeth Dawson-Hahn   +10 more
doaj   +1 more source

The IoT Rapid-Proto Labs Value Proposition for Start-ups and SMEs [PDF]

, 2020
The objective of the study is to identify and suggest relevant elements of value on which the IoT Rapid-Proto Labs will focus to correctly structure, define and create a value proposition for the start-ups and SME’s segments. Hence, the study develops on
Peña Archila, Jorge Andres
core  

Clinical relevance and treatment possibilities of bipolar rapid cycling [PDF]

, 2002
Bipolar rapid cycling (RC) is defined as 4 or more affective episodes within 1 year. It has been postulated that RC is related to a poor response to lithium, to the same extent as mixed episodes or other atypical symptoms of the illness.
Amann, B., Dittmann, Sandra, Amann, Benedikt, Grunze, Heinz, Walden, Jörg   +4 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Beyond Spheres: Evaluating Gold Nano-Flowers and Gold Nano-Stars for Enhanced Aflatoxin B1 Detection in Lateral Flow Immunoassays

Biosensors
The lateral flow immunoassay (LFIA) is a widely utilized, rapid diagnostic technique characterized by its short analysis duration, cost efficiency, visual result interpretation, portability and suitability for point-of-care applications.
Vinayak Sharma, Bilal Javed, Hugh J. Byrne, Furong Tian   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

An FIA-MS Method for Rapid Coffee Adulteration Detection: A Comparative Study with a Non-Targeted LC-MS Approach

Foods
Coffee adulteration is a growing concern in the food industry due to economic and quality implications. This study evaluates a rapid, non-targeted fingerprinting method based on flow injection analysis–mass spectrometry (FIA-MS) for detecting common ...
Nerea Núñez, Javier Saurina, Oscar Núñez   +2 more
doaj   +1 more source