Results 81 to 90 of about 77,020 (217)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Clinical characteristics and pathogenesis of rapid and precipitous labor in women [PDF]

Гинекология, 2014
Article presents retrospective-prospective analysis of pregnancy course and outcomes of rapid and precipitous labor in 115 women with term pregnancies. Morphological and immunohistochemical characterics of the cervix were studied.
M E Gelezova, L I Malceva, T P Zephirova
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Spatial assessment of water quality in Mananga River in Talisay City, Cebu, Philippines

Results in Engineering
This paper focuses on the degradation of water quality in the Mananga River and aims to analyze spatial changes for the recommendation for rehabilitation.
Ronnel S. Melad, Raphael Luis V. Nonato, Dale Joseph Salazar, Mayzonee V. Ligaray, Angelo Earvin Sy Choi   +4 more
doaj   +1 more source

A sensitive immunoassay for the rapid analysis of fluopicolide

Talanta
The analysis of chemical xenobiotics in human, food, and environmental samples has become a global priority. Consequently, both public and private laboratories require rapid, cost-effective analytical methods for quality and safety control. Fluopicolide, a fungicide used to combat plant diseases, poses potential toxicological risks to humans and ...
José V. Gimeno-Alcañiz, Antonio Abad-Fuentes, Ismael Navarro-Fuertes, Hadyn Duncan, Daniel López-Puertollano, Antonio Abad-Somovilla, Josep V. Mercader   +6 more
openaire   +4 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Planning for and Assessing Rigor in Rapid Qualitative Analysis (PARRQA): a consensus-based framework for designing, conducting, and reporting

Implementation Science
Background The use of rapid qualitative methods has increased substantially over the past decade in quality improvement and health services research.
Christine P. Kowalski, Andrea L. Nevedal, Erin P. Finley, Jessica P. Young, Allison A. Lewinski, Amanda M. Midboe, Alison B. Hamilton   +6 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

[Rapid immunoenzyme analysis].

Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1985
A variant of the immunoenzyme assay, reducing the duration of the assay procedure by 3 hours in comparison with the standard technique, is presented. This rapid variant is sufficiently sensitive and reproducible.
Z M, Andreeva, V A, Nikonova, T S, Shobukhova, L I, Vaneeva, N F, Iankina   +4 more
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source