Results 41 to 50 of about 6,732,782 (269)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

RAPID FORESIGHT: MODERN ADULT EDUCATION TECHNOLOGY

open access: yesВестник Северо-Кавказского федерального университета, 2022
The article discusses the issues of adult education in the framework of the developing trend of reforming the system of additional education. The possibility of using in training a new active innovative method - rapidforesight.
M. Erentsenova, S. Bludov
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Donors and developers in population communication [PDF]

open access: yes, 1977
"This project was supported by the Office of Population, U.S. Agency for International Development, AID/csd-1059."For more about the East-West Center, see http://www.eastwestcenter.org/This paper is a review of technical and economic assistance in the ...
East-West Communication Institute   +1 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Customer perception of AI-supported communication in insurance: a Rapid Review

open access: yesEntrepreneurship and Sustainability Issues
Digitalization in the insurance industry has significantly accelerated in recent years, accompanied by a growing use of artificial intelligence in the automation of customer communication.
Dana Jašková, Katarína Kráľová
doaj   +1 more source

On Some Features of Text Bonds Functioning in Internet Communication (by Example of Bonds TAKIM OBRAZOM and ITAK)

open access: yesНаучный диалог, 2019
The article is devoted to the analysis of the functioning of text bonds itak and takim obrazom ‘so; thus’ in Internet communication. The relevance of the study is determined by the rapid development of Internet communication, which led to rapid changes ...
P. M. Tyurin
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

OrganiZational communication and organiSational communication: Binaries and the fragments of a field [PDF]

open access: yes, 2009
In this paper, I employ personal narrative to help cast light on connections and tensions between organiZational communication research, as produced in the United States, and organiSational communication research, as produced in Aotearoa New Zealand.
Ganesh, Shiv
core  

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