Melatonin for rapid eye movement sleep behavior disorder in Parkinson's disease : a randomised controlled trial [PDF]
Movement Disorders, 2019 Background Melatonin may reduce REM-sleep behavior disorder (RBD) symptoms in Parkinson's disease (PD), though robust clinical trials are lacking. Objective To assess the efficacy of prolonged-release (PR) melatonin for RBD in PD.
Coeytaux Jackson, Alessandra +10 more
core +2 more sources
Rapid eye movement sleep without Atonia in healthy university students without clinical rapid eye movement sleep behavior disorder [PDF]
BMC NeurologyBackground Rapid eye movement (REM) sleep without atonia (RWA) on polysomnography (PSG) is an essential finding for the diagnosis of idiopathic REM sleep behavior disorder (RBD).
Yuka Kiyohara +10 more
doaj +2 more sources
Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction. [PDF]
PLoS ONE, 2017 Insomnia is the most common sleep complaint which occurs due to difficulty in falling asleep or maintaining it. Most of currently available drugs for insomnia develop dependency and/or adverse effects.
Mahesh K Kaushik +4 more
doaj +3 more sources
Narcolepsy and rapid eye movement sleep. [PDF]
J Sleep ResSummarySince the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Biscarini F +4 more
europepmc +4 more sources
Movement Disorders, 2023 Misfolded α‐synuclein (αSyn) aggregates (αSyn‐seeds) in cerebrospinal fluid (CSF) are biomarkers for synucleinopathies such as Parkinson's disease (PD).
L. Concha-Marambio +14 more
semanticscholar +1 more source
Speech Biomarkers in Rapid Eye Movement Sleep Behavior Disorder and Parkinson Disease
Annals of Neurology, 2021 This multilanguage study used simple speech recording and high‐end pattern analysis to provide sensitive and reliable noninvasive biomarkers of prodromal versus manifest α‐synucleinopathy in patients with idiopathic rapid eye movement sleep behavior ...
J. Rusz +26 more
semanticscholar +1 more source
Dyscoordination of Non-Rapid Eye Movement Sleep Oscillations in Autism Spectrum Disorder.
Sleep, 2022 STUDY OBJECTIVES Converging evidence from neuroimaging, sleep, and genetic studies suggests that dysregulation of thalamocortical interactions mediated by the thalamic reticular nucleus (TRN) contribute to autism spectrum disorder (ASD).
D. Mylonas +8 more
semanticscholar +1 more source
Movement Disorders, 2023 Correct diagnosis of rapid eye movement sleep behavior disorder (RBD) is critical due to its link to α‐synucleinopathies and risk of injuries and requires video‐polysomnography (V‐PSG).
A. Stefani +14 more
semanticscholar +1 more source
Polysomnographic Assessment of Sleep Comorbidities in Drug-Naïve Narcolepsy-Spectrum Disorders--A Japanese Cross-Sectional Study. [PDF]
PLoS ONE, 2015 This is a large cross-sectional study which aimed to investigate comorbidity rate, degree of sleep-related breathing disorder, polysomnigraphically diagnosible rapid eye movement sleep behavior disorder/rapid eye movement sleep without atonia and ...
Taeko Sasai-Sakuma +2 more
doaj +1 more source
The Correlation between Clinical Variables and Sleep Onset Rapid Eye Movement Period Frequencies in Narcoleptic Patients [PDF]
Sleep Medicine Research, 2010 Background and Objective A diagnosis of narcolepsy is defined by less than 8 minutes of mean sleep latency, and two or more sleep onset rapid eye movement periods on the Multiple Sleep Latency Test.
Jin Hwa Jeong +10 more
doaj +1 more source