Results 1 to 10 of about 227,844 (315)

Speech Biomarkers in Rapid Eye Movement Sleep Behavior Disorder and Parkinson Disease [PDF]

Annals of Neurology, 2021
This multilanguage study used simple speech recording and high‐end pattern analysis to provide sensitive and reliable noninvasive biomarkers of prodromal versus manifest α‐synucleinopathy in patients with idiopathic rapid eye movement sleep behavior ...
J. Rusz, Jan Hlavnička, Michal Novotný, T. Tykalová, A. Pelletier, J. Montplaisir, J. Gagnon, P. Dušek, A. Galbiati, S. Marelli, P. Timm, L. Teigen, A. Janzen, Mahboubeh Habibi, A. Stefani, E. Holzknecht, K. Seppi, Elisa Evangelista, A. Rassu, Y. Dauvilliers, B. Högl, W. Oertel, E. S. St. Louis, L. Ferini-Strambi, E. Růžička, R. Postuma, K. Šonka   +26 more
semanticscholar   +2 more sources

Melatonin for rapid eye movement sleep behavior disorder in Parkinson's disease : a randomised controlled trial [PDF]

Movement Disorders, 2019
Background Melatonin may reduce REM-sleep behavior disorder (RBD) symptoms in Parkinson's disease (PD), though robust clinical trials are lacking. Objective To assess the efficacy of prolonged-release (PR) melatonin for RBD in PD.
Coeytaux Jackson, Alessandra, Fang, Bernard A.M., Gilat, Moran, Grunstein, Ron R., Hall, Julie, Hammond, Deborah, Lewis, Simon J. G., Marshall, Nathaniel S., Mullins, Anna E., Wong, Keith K.H., Yee, Brendon J.   +10 more
core   +2 more sources

Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction. [PDF]

PLoS ONE, 2017
Insomnia is the most common sleep complaint which occurs due to difficulty in falling asleep or maintaining it. Most of currently available drugs for insomnia develop dependency and/or adverse effects.
Mahesh K Kaushik, Sunil C Kaul, Renu Wadhwa, Masashi Yanagisawa, Yoshihiro Urade   +4 more
doaj   +3 more sources

Rapid eye movement sleep without Atonia in healthy university students without clinical rapid eye movement sleep behavior disorder [PDF]

BMC Neurology
Background Rapid eye movement (REM) sleep without atonia (RWA) on polysomnography (PSG) is an essential finding for the diagnosis of idiopathic REM sleep behavior disorder (RBD).
Yuka Kiyohara, Hajime Kumagai, Mitsuo Hayashi, Akiko Kanoh, Kana Asada, Misao Yokoyama, Moe Yamagami, Kengo Kawaguchi, Hiroyuki Sawatari, Noriyuki Konishi, Toshiaki Shiomi   +10 more
doaj   +2 more sources

Narcolepsy and rapid eye movement sleep. [PDF]

J Sleep Res
SummarySince the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Biscarini F, Barateau L, Pizza F, Plazzi G, Dauvilliers Y.   +4 more
europepmc   +4 more sources

Accurate Detection of α‐Synuclein Seeds in Cerebrospinal Fluid from Isolated Rapid Eye Movement Sleep Behavior Disorder and Patients with Parkinson's Disease in the DeNovo Parkinson (DeNoPa) Cohort

Movement Disorders, 2023
Misfolded α‐synuclein (αSyn) aggregates (αSyn‐seeds) in cerebrospinal fluid (CSF) are biomarkers for synucleinopathies such as Parkinson's disease (PD).
L. Concha-Marambio, Sandrina Weber, C. Farris, Mohammed Dakna, Elisabeth Lang, T. Wicke, Yihua Ma, Maritta Starke, J. Ebentheuer, F. Sixel-Döring, M. Muntean, Sebastian Schade, C. Trenkwalder, C. Soto, B. Mollenhauer   +14 more
semanticscholar   +1 more source

Dyscoordination of Non-Rapid Eye Movement Sleep Oscillations in Autism Spectrum Disorder.

Sleep, 2022
STUDY OBJECTIVES Converging evidence from neuroimaging, sleep, and genetic studies suggests that dysregulation of thalamocortical interactions mediated by the thalamic reticular nucleus (TRN) contribute to autism spectrum disorder (ASD).
D. Mylonas, Sasha Machado, O. Larson, Rudra Patel, Roy Cox, M. Vangel, K. Maski, R. Stickgold, D. Manoach   +8 more
semanticscholar   +1 more source

Low Specificity of Rapid Eye Movement Sleep Behavior Disorder Questionnaires: Need for Better Screening Methods

Movement Disorders, 2023
Correct diagnosis of rapid eye movement sleep behavior disorder (RBD) is critical due to its link to α‐synucleinopathies and risk of injuries and requires video‐polysomnography (V‐PSG).
A. Stefani, M. Serradell, E. Holzknecht, C. Gaig, Abubaker Ibrahim, P. Marrero, M. Cesari, L. Pérez-Carbonell, E. Brandauer, A. Fernández-Arcos, M. Bergmann, Núria Matos, J. Santamaria, B. Högl, Á. Iranzo   +14 more
semanticscholar   +1 more source

Polysomnographic Assessment of Sleep Comorbidities in Drug-Naïve Narcolepsy-Spectrum Disorders--A Japanese Cross-Sectional Study. [PDF]

PLoS ONE, 2015
This is a large cross-sectional study which aimed to investigate comorbidity rate, degree of sleep-related breathing disorder, polysomnigraphically diagnosible rapid eye movement sleep behavior disorder/rapid eye movement sleep without atonia and ...
Taeko Sasai-Sakuma, Akihiko Kinoshita, Yuichi Inoue   +2 more
doaj   +1 more source

Lower slow wave sleep and rapid eye‐movement sleep are associated with brain atrophy of AD‐vulnerable regions [PDF]

Alzheimers Dement
Cho G, Mecca A, Buxton O, Liu X, Miner B.   +4 more
europepmc   +4 more sources