Results 141 to 150 of about 226,654 (353)

Study on the relationship between sleep–wake states and prognosis in patients with intracranial arterial stenosis and ischemic stroke

Frontiers in Neurology
ObjectiveTo evaluate the influence of the sleep–wake state on the prognosis of patients with ischemic stroke.MethodsConsecutive patients with intracranial ischemic stroke due to arterial stenosis were included (198 cases).
Xiaodong Yuan, Xiaodong Yuan, Jing Xue, Jing Xue, Yongshan Fu, Yongshan Fu, Ya Ou, Ying Zhao, Ying Zhao, Cuiping Yan, Cuiping Yan, Pingshu Zhang, Pingshu Zhang   +12 more
doaj   +1 more source

T. rex cognition was T. rex‐like—A critical outlook on diverging views of the neurocognitive evolution in dinosaurs

The Anatomical Record, EarlyView.
Abstract A recent debate has emerged between Caspar et al. (2024) and Herculano‐Houzel (2023) on inferring extinct dinosaur cognition by estimating brain neuron counts. While thought‐provoking, the discussion largely overlooks the function of cognition, as well as partly neglects the difficulties involved in estimating neuron numbers, which according ...
Thomas Rejsenhus Jensen, Ivo Jacobs, Kristina Kverková, Lona Lalić, Alexandra Polonyiová, Patrik Stehlík, Stephan A. Reber, Mathias Osvath   +7 more
wiley   +1 more source

Atypical Visually Guided Precision Grip Control in Middle‐Aged and Older Autistic Adults

Autism Research, EarlyView.
ABSTRACT Sensorimotor impairments are well documented in autism spectrum disorder (ASD). However, little is known about how these difficulties present in middle‐aged and older autistic adults or how they relate to demographic factors and autistic traits.
Zheng Wang, Hang Qu, Danielle Christensen, Hanna M. Gemmell, Ellen M. Parks, Kyla E. Wetherington, Ann‐Marie Orlando, Regilda A. Romero, Bikram Karmakar, David E. Vaillancourt   +9 more
wiley   +1 more source

Electroencephalogram paroxysmal theta characterizes cataplexy in mice and children [PDF]

, 2017
Astute control of brain activity states is critical for adaptive behaviours and survival. In mammals and birds, electroencephalographic recordings reveal alternating states of wakefulness, slow wave sleep and paradoxical sleep (or rapid eye movement ...
Dellepiane, Jose M., Emmenegger, Yann, Franken, Paul, Jimenez, Sonia, Plazzi, Giuseppe, Tafti, Mehdi, Vandi, Stefano, Vassalli, Anne   +7 more
core  

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

Marine silicon for biomedical sustainability

BMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han, Zhibo Yang, Wei Xia, Chengtie Wu   +3 more
wiley   +1 more source

The myth of the metabolic baseline: sleep–wake cycles undermine a foundational assumption in organismal biology

Biological Reviews, EarlyView.
ABSTRACT Basal and standard metabolic rate (BMR and SMR) are cornerstones of physiological ecology and are assumed to be relatively fixed intrinsic properties of organisms that represent the minimum energy required to sustain life. However, this assumption is conceptually flawed. Many core maintenance processes underlying SMR are temporally partitioned
Helena Norman, Daphne Cortese, Amelia Munson, Jan Lindström, Shaun S. Killen   +4 more
wiley   +1 more source

An Excitatory Circuit in the Perioculomotor Midbrain for Non-REM Sleep Control. [PDF]

, 2019
The perioculomotor (pIII) region of the midbrain was postulated as a sleep-regulating center in the 1890s but largely neglected in subsequent studies.
Barger, Zeke, Chung, Shinjae, Dan, Yang, Ding, Xinlu, Hu, Fei, Li, Shangzhong, Palmiter, Richard D, Ren, Yulan, Weber, Franz, Zhang, Zhe, Zhong, Peng   +10 more
core  

Chronic insomnia, REM sleep instability and emotional dysregulation: A pathway to anxiety and depression? [PDF]

Summary: The world‐wide prevalence of insomnia disorder reaches up to 10% of the adult population. Women are more often afflicted than men, and insomnia disorder is a risk factor for somatic and mental illness, especially depression and anxiety disorders.
Baglioni, Chiara, Benz, Fee, Berger, Mathias, Domschke, Katharina, Dressle, Raphael J., Feige, Bernd, Hertenstein, Elisabeth, Johann, Anna F., Krone, Lukas, Nissen, Christoph, Palagini, Laura, Perlis, Michael L., Riemann, Dieter, Spiegelhalder, Kai   +13 more
core   +2 more sources