Results 121 to 130 of about 186,072 (301)

Valuing the SDG Prize in Food and Agriculture: Unlocking Business Opportunities to Accelerate Sustainable and Inclusive Growth [PDF]

open access: yes, 2016
Business opportunities in the implementation of the SDGs related to food could be worth over US$2.3 trillion annually for the private sector by 2030. Investment required to achieve these opportunities is approximately US$320 billion per year.These 14 ...

core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Dynamic Vortex Height Evolution During Tropical Cyclone Rapid Intensification

open access: yesJournal of Geophysical Research: Atmospheres
AbstractThe vertical structure of the tropical cyclone (TC) vortex can be quantified throughout the TC life cycle via the dynamic height of the vortex (DHOV) metric, which is sensitive to the rate of decay of the tangential wind field with height. Observed storms always possessed a high DHOV value prior to periods of rapid intensification (RI).
Alexander J. DesRosiers, Michael M. Bell
openaire   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Dynamic mechanism for the evolution and rapid intensification of Typhoon Hato (2017)

open access: yesAtmospheric Science Letters, 2019
This study investigated the evolution of Typhoon Hato (1713) and analyzed the inner dynamics of its rapid intensification. The moving path of Hato was controlled by the southwestern part of the western Pacific subtropical high which extended westward ...
Renwen Zhang, Jingliang Huangfu, Ting Hu
doaj   +1 more source

Monitoring tropical cyclone intensity using wind fields derived from short-interval satellite images [PDF]

open access: yes
Rapid scan visible images from the Visible Infrared Spin Scan Radiometer sensor on board SMS-2 and GOES-1 were used to derive high resolution upper and lower tropospheric environmental wind fields around three western Atlantic tropical cyclones (1975-78).
Gentry, R. C., Rodgers, E. B.
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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