Results 151 to 160 of about 186,072 (301)

Importance of short interval (six hour) intensity changes in understanding the rapid intensification/weakening trends of tropical cyclones

open access: yesTropical Cyclone Research and Review
The intensity of tropical cyclones (TCs) varies at different rates throughout their life cycle. Among them, rapid intensification (RI, intensity change ≥30 knots/24 h) and rapid weakening (RW, intensity change ≤ −30 knots/24 h) of TCs are extremely ...
Sreenivas Pentakota   +5 more
doaj   +1 more source

The inter-linkages between rapid growth in livestock production, climate change, and the impacts on water resources, land use, and deforestation [PDF]

open access: yes
Livestock systems globally are changing rapidly in response to human population growth, urbanization, and growing incomes. This paper discusses the linkages between burgeoning demand for livestock products, growth in livestock production, and the impacts
Herrero, Mario, Thornton, Philip K.
core  

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

Satellite based analysis of rapid intensification of Super Cyclone Amphan

open access: yesMAUSAM
Tropical Cyclones (TCs) are formidable natural hazards with destructive impacts on life and property along the tropical belt. TCs are responsible for multiple hazards such as riverine and urban floods, extreme winds, and lightning, storm surge significantly amplifying the threats they pose.
Chinmay Khadke   +2 more
openaire   +1 more source

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro   +10 more
wiley   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

POPULATION PRESSURE, MARKET ACCESS AND FOOD SECURITY IN THE UPLANDS OF NORTHERN VIETNAM: A MICRO-ECONOMIC ANALYSIS [PDF]

open access: yes
Upland areas in Vietnam account for two-thirds of its natural area and one-third of its population. These uplands are characterized by heterogeneous and fragile ecosystems, a high incidence of poverty, severe deforestation and soil degradation.
Khiem, Nguyen Tri, Pandey, Sushil
core   +1 more source

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas   +39 more
wiley   +1 more source

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