Results 1 to 10 of about 1,789,575 (241)

Potential Analysis Of Flexible Small Series Production Of Spare Parts By Direct Polymer Additive Tooling

open access: yesProceedings of the Conference on Production Systems and Logistics, 2021
In recent decades, there has been an increasing creation of vehicle model variants and product individualization for customer needs. There is a need for a greater variety of spare parts which is leading to high requirements on their logistics.
Schuh, Günther   +7 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Procedure for Reconstruction, Modeling, and Fabrication Using Additive and Rapid Tooling Methods of a Training Model for Transsphenoidal Surgery

open access: yesJournal of Manufacturing and Materials Processing
The endoscopic transsphenoidal approach (ETA) is a novel approach used by neurosurgeons and otolaryngologists to treat pituitary adenoma, and it has a long learning curve.
Giacomo Santona   +3 more
doaj   +1 more source

Rapid Tools Compensation in Sheet Metal Stamping Process

open access: yesMATEC Web of Conferences, 2016
The sudden growth of additive manufacturing is generating a renovated interest towards the field of rapid tooling. We propose a geometrical compensation method for rapid tools made by thermoset polyurethane.
Iorio Lorenzo   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Performance Analysis of Enhanced 3D Printed Polymer Molds for Metal Injection Molding Process

open access: yesMetals, 2018
Conventionally, molds for metal injection molding (MIM) process are fabricated using metallic materials using conventional machining processes. Machined metal molds are resilient and therefore could be suitable for mass production of MIM parts.
Khurram Altaf   +8 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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