Results 111 to 120 of about 405,179 (293)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Smartphone-based, rapid, wide-field fundus photography for diagnosis of pediatric retinal diseases [PDF]

open access: yes, 2019
PurposeAn important, unmet clinical need is for cost-effective, reliable, easy-to-use, and portable retinal photography to evaluate preventable causes of vision loss in children.
Besirli, Cagri G.   +10 more
core   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Knowledge Model Based Intelligent Visual Identification of Catenary Defects

open access: yesKongzhi Yu Xinxi Jishu, 2021
As high speed rails increase in mileage and operational intensity, the use of onboard video to conduct normalized and intelligent inspections of the service status of key catenary facilities under the condition of limited operation and maintenance ...
TANG Peng   +5 more
doaj  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Equivalence of background and bleaching desensitization in isolated rod photoreceptors of the larval tiger salamander. [PDF]

open access: yes, 1996
Psychophysical experiments have shown an equivalence between sensitivity reduction by background light and by bleaches for the human scotopic system.
Cornwall, MC, Fain, GL, Jones, GJ
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz   +11 more
wiley   +1 more source

Designing a Computerized Neuro-Cognitive Program for Early Diagnosing Children at Risk for Dyslexia

open access: yesIranian Rehabilitation Journal, 2017
Objectives: The aim of this research is to design a neuro-cognitive program, based on dysfunctions and alterations of some neural circuits in dyslexics.
Mona Delavarian   +3 more
doaj  

Building Distribution and Spatial Constraints from Perspectives of Tsunami Inundation at a Small Island Context: A Study Case of Sabang-Aceh, 20 Years after the 2004 Aceh Tsunami

open access: yesJournal of the Civil Engineering Forum
In the aftermath of the devastating 2004 Indian Ocean tsunami, the Indonesian government implemented disaster mitigation measures through improved spatial planning, particularly in settlement areas.
Syamsidik   +7 more
doaj   +1 more source

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