Evolutionary insights into Na<sup>+</sup>/K<sup>+</sup>-ATPase-mediated toxin resistance in the Crested Serpent-eagle preying on introduced cane toads in Okinawa, Japan. [PDF]
Tobe A +4 more
europepmc +1 more source
Evaluating the demographic impacts of the highly pathogenic avian influenza panzootic
Our findings demonstrate that the HPAIV panzootic can cause rapid and long‐lasting impacts on the dynamics of long‐lived species. This raises major concerns for the conservation and long‐term viability of the many severely affected long‐lived species worldwide.
Jaume A. Badia‐Boher +6 more
wiley +1 more source
Inhibition of TRAF3IP2 Modulates NAMPT and NAD Metabolism in Glioblastoma. [PDF]
Willingham K +8 more
europepmc +1 more source
Pruning for biodiversity: Drivers of cavity formation and use in Mediterranean holm oak woodlands
Our study emphasizes the role of both tree and cavity age in the long‐term establishment of cavity‐dependent vertebrates in holm oak woodlands. In the context of climate change—where holm oak trees are expected to replace more mesic, soft‐wooded tree species in the Mediterranean region—the persistence of cavity‐dependent vertebrate biodiversity will ...
Iván de la Hera, Jesús M. Avilés
wiley +1 more source
Targeting TRAF3IP2 disrupts cellular energetics through inhibition of NAMPT in triple negative breast cancer. [PDF]
Willingham K +7 more
europepmc +1 more source
Captive birds at the National Zoological Garden in South Africa harbor diverse haemosporidian parasite species and lineages. This might compromise conservation efforts of threatened species. ABSTRACT Avian haemosporidian infections have been associated with disease outbreaks in zoos and rehabilitation centers globally. This study aimed to determine the
Realeboga Masego Gaorekwe +3 more
wiley +1 more source
Missense variant in TTBK2 kinase domain causes loss of function and impaired protein phosphorylation. [PDF]
Felício D +10 more
europepmc +1 more source
Epigenetic Age Prediction Using N6‐Methyladenine in the Buff‐Tailed Bumblebee (Bombus terrestris)
In bumblebees, age‐related patterns of N6‐methyladenine can be used to build accurate epigenetic clocks that are responsive to lifespan‐extending interventions, providing the first proof of concept that this epigenetic mark can be used as a biomarker of aging.
Thibaut Renard +2 more
wiley +1 more source
Rulers of the Open Sky at Risk: Climate-Driven Habitat Shifts of Three Conservation-Priority Raptors in the Eastern Himalayas. [PDF]
Mahananda P +6 more
europepmc +1 more source
Summary of SLCO1B1 impact on methotrexate treatment of juvenile idiopathic arthritis, and the promise of SLCO1B1‐guided dosing. Polymorphisms to the SLCO1B1 gene influence MTX PK and JIA treatment outcomes. Preclinical studies demonstrate reduced MTX exposure and treatment efficacy with the SLCO1B1*14 allele linked to increased hepatic OATP1B1 ...
Felicia Gooden +10 more
wiley +1 more source

