Results 31 to 40 of about 17,277 (262)
Random ssDNA–SWCNT(single strand DNA‐single walled carbon nanotube) library is functionally screened and evolved using high‐throughput 3D prostate tumor spheroids via iterative positive and negative selection, enabling the identification of NIR‐II fluorescent ssDNA‐SWCNT nanoprobe specific for prostate cancer.
Dakyeon Lee +8 more
wiley +1 more source
Constitutive PRKCN expression is driven by super‐enhancers and modulated by NF‐κB signaling in multiple myeloma (MM). PRKCN activates mTORC1/2‐IRF4 signaling axis and favors tumor cell growth independently of its kinase activity. IRF4 reciprocally promotes PRKCN transcription, creating a feed‐forward loop.
Koukou Tang +12 more
wiley +1 more source
PDK1 phosphorylates multiple substrates including Akt by PIP3-dependent mechanisms. In this report we provide evidence that in prostate cancer cells stimulated with activated α2-macroglobulin (α2M*) PDK1 phosphorylates Akt in the T-loop at Thr(308) by ...
Uma Kant Misra, Salvatore Vincent Pizzo
doaj +1 more source
Bioinspired Adaptive Leg‐Claw Enables Robust Perching and Grasping for UAVs
Inspired by owl limb morphology and bat roosting behavior, this study presents a bioinspired adaptive leg‐claw mechanism that enables UAVs to perform robust and versatile perching and grasping. The design integrates a four‐link tibial structure, tension‐driven deformable feet, and active control, enabling stable perching on various branches and ...
Tianyu Cheng +6 more
wiley +1 more source
Guidelines for the Anti‐Obesity Assays of Food Bioactives in Caenorhabditis elegans
This Guideline uses Caenorhabditis elegans as a model organism to systematically explain and summarize the research strategies and experimental methods for the anti‐obesity effects of food bioactives. ABSTRACT The obesity has become a global public health problem and is closely related to a variety of chronic diseases.
Rui Lu
wiley +1 more source
Status and Trends in the Eastern Imperial Eagle Population Between 1977 and 2018 in Slovakia
In Slovakia, two subpopulations of the Eastern Imperial Eagle (Aquila heliaca) – Western and Eastern Slovakian – are recognized with a distance between them of 200–300 km.
Jozef Chavko +5 more
doaj
CTNS mutations in publicly-available human cystinosis cell lines
Patient samples play an important role in the study of inherited metabolic disorders. Open-access biorepositories distribute such samples. Unfortunately, not all clinically-characterized samples come with reliable genotype information.
Artem Zykovich +3 more
doaj +1 more source
Gaze‐Engineered 3D Augmented Reality
Augmented Reality (AR) systems serve as a critical interface bridging users with the metaverse. This study explores the application of human factors engineering in metaverse development, specifically investigating the integration of eye‐tracking technology to enhance AR display performance.
Naiqin Zhao +3 more
wiley +1 more source
Nest box use by American Kestrels and other cavity-nesting birds during the nonbreeding season
Nest boxes are posted to provide breeding sites for cavity-nesting birds but less is known about their function in the nonbreeding season, when nest boxes may become important roost sites.
Caitlin M. Davis +2 more
doaj +1 more source
Hematopoietic stem cells (HSCs) ensure the lifelong production of blood cells throughout a lifetime. Latexin (Lxn) is thought to have a tumor suppressor role and endogenously down-regulate the number of HSCs via increased apoptosis.
Gokhan Pektas +3 more
doaj +1 more source

