Results 31 to 40 of about 59,664 (266)
Raptor hunted by caspases [PDF]
Cell Death & Disease, 2016 Emergence of survival strategies is a key step for organisms during evolution. The capacity to adapt from nutrient-rich to nutrient-poor environments led to the appearance of protein complexes regulating anabolic and catabolic pathways. The evolutionarily conserved kinase mTOR (mechanistic target of rapamycin) emerged as a crucial and central protein ...
R Martin, M Thome, F Martinon, N Fasel
openaire +5 more sources
Nonlocomotory Robotic Strategies for Dynamic Rotation Control in Terrestrial Robots: A Review
Advanced Robotics Research, EarlyView.Terrestrial robots increasingly require rapid body rotation to maintain stability and agility in complex environments. This review shows nonlocomotory rotational control strategies that operate without ground contact, including reaction wheels, tails, bars, limbs, and thrusters.
Y. Liang +14 more
wiley +1 more source
PLoS ONE, 2014 PDK1 phosphorylates multiple substrates including Akt by PIP3-dependent mechanisms. In this report we provide evidence that in prostate cancer cells stimulated with activated α2-macroglobulin (α2M*) PDK1 phosphorylates Akt in the T-loop at Thr(308) by ...
Uma Kant Misra, Salvatore Vincent Pizzo
doaj +1 more source
The Bald And Golden Eagle Protection Act, Species-Based Legal Protection And The Danger Of Misidentification [PDF]
Potchefstroom Electronic Law Journal, 2015 The Bald and Golden Eagle Protection Act of 1940 bestows legal protection on two North American eagle species in the United States of America.
Johann C Knobel
doaj +1 more source
Advanced Science, EarlyView.Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon +6 more
wiley +1 more source
CTNS mutations in publicly-available human cystinosis cell lines
Molecular Genetics and Metabolism Reports, 2015 Patient samples play an important role in the study of inherited metabolic disorders. Open-access biorepositories distribute such samples. Unfortunately, not all clinically-characterized samples come with reliable genotype information.
Artem Zykovich +3 more
doaj +1 more source
The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest
Cell Reports, 2020 Summary: mTOR is a serine/threonine kinase and a master regulator of cell growth and proliferation. Raptor, a scaffolding protein that recruits substrates to mTOR complex 1 (mTORC1), is known to be phosphorylated during mitosis, but the significance of ...
Mohamed Moustafa-Kamal +8 more
doaj +1 more source
The Anatomical Record, EarlyView.Abstract Muscle architecture is a major determinant of muscle performance and, in mammalian lineages, has been correlated with both feeding ecology and locomotor behaviors. Over the past decade, contrast‐enhanced micro‐CT (DiceCT) has emerged as an alternative to traditional dissection‐based measurement.
Aleksandra Ratkiewicz +5 more
wiley +1 more source
Status and Trends in the Eastern Imperial Eagle Population Between 1977 and 2018 in Slovakia
Пернатые хищники и их охрана, 2018 In Slovakia, two subpopulations of the Eastern Imperial Eagle (Aquila heliaca) – Western and Eastern Slovakian – are recognized with a distance between them of 200–300 km.
Jozef Chavko +5 more
doaj
Transcriptional Regulation of NK Cell Development by mTOR Complexes
Frontiers in Cell and Developmental Biology, 2020 The mechanistic target of Rapamycin (mTOR) is essential for multiple cellular processes. The unique roles of mTOR complex 1 (mTORC1) or mTOR2 in regulating immune functions are emerging.
Chao Yang +5 more
doaj +1 more source