Results 261 to 270 of about 407,179 (345)

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You   +12 more
wiley   +1 more source

A Microfluidic Digital Shutter of Liquid–Liquid Interface for Fabrication of Multifaceted Hydrogel Microfiber Structure

open access: yesAdvanced Science, EarlyView.
A programmable passive digital shutter based on multiphase liquid–liquid interface dynamics is introduced for precise fabrication of hydrogel microfibers. By modulating the shutter operation, microfibers with tunable geometry—including linear, helical, tadpole‐like, and spherical forms—are produced.
Dongrui Zhang   +14 more
wiley   +1 more source

Electrochemiluminescence Drives Photodynamic Therapy In Vivo

open access: yesAdvanced Science, EarlyView.
Electrochemiluminescence (ECL)‐driven photodynamic therapy (PDT) for in vivo cancer treatment is reported for the first time. The flexible ECL patch exhibits stable and intense luminance under alternating current voltage, enabling efficient photosensitization to generate reactive oxygen species that damage cancer cells, thus leading to significant ...
Jia‐Bao Lin   +5 more
wiley   +1 more source

Coordination-Locked Engineering to Achieve Narrowband Room Temperature Phosphorescence in Non-Rare Earth Metal-Organic Frameworks. [PDF]

open access: yesAdv Sci (Weinh)
Zhang W   +11 more
europepmc   +1 more source

Construction of PANoptosis‐Inhibiting Carbonized Polymer Dots via Machine Learning Potential for Mitigating Chemodrug‐Induced Nephrotoxicity

open access: yesAdvanced Science, EarlyView.
An enhanced sampling method is developed for molecular dynamics based on trained machine learning force fields to guide the construction of PANoptosis‐inhibiting carbonized polymer dots (Lu‐CDs) derived from a flavonoid compound for treating chemodrug‐induced nephrotoxicity.
Xinchen Liu   +8 more
wiley   +1 more source

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