Results 171 to 180 of about 11,812,623 (407)

Unsupervised non‐small cell lung cancer tumor segmentation using cycled generative adversarial network with similarity‐based discriminator

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Tumor segmentation is crucial for lung disease diagnosis and treatment. Most existing deep learning‐based automatic segmentation methods rely on manually annotated data for network training. Purpose This study aims to develop an unsupervised tumor segmentation network smic‐GAN by using a similarity‐driven generative adversarial ...
Chengyijue Fang   +2 more
wiley   +1 more source

Adult sickle cell disease and SARS-CoV-2: an increasingly common comorbidity for a rare disease

open access: yesItalian Journal of Medicine
Sickle cell disease (SCD) is a collection of genetic lesions that manifest in the diminished effectiveness of hemoglobin. We collected and reviewed the recent and extant literature on SARS-CoV-2 (COVID-19) and SCD.
Michaela Boggan   +14 more
doaj   +1 more source

The Caregiving Experiences of Fathers and Mothers of Children With Rare Diseases in Italy: Challenges and Social Support Perceptions

open access: yesFrontiers in Psychology, 2019
Family caregiving is a growing phenomenon with the increased prevalence of chronic illness and shorter hospitalizations. Rare diseases pose significant challenges not only to patients living with these kinds of pathologies but also to those who care for ...
P. Cardinali, L. Migliorini, N. Rania
semanticscholar   +1 more source

Radiotherapy medical physics in the Philippines: A contemporary overview

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose With cancer ranking as the third leading cause of death in the Philippines and a disparity in healthcare resources across regions, this research aimed to assess the state of radiotherapy medical physics in the country. Methodology The study utilized a comprehensive online survey with 94 structured questions answered by 19 clinics ...
John Paul C. Cabahug   +4 more
wiley   +1 more source

ZIKQ: An innovative centile chart method for utilizing natural history data in rare disease clinical development [PDF]

open access: yes
Utilizing natural history data as external control plays an important role in the clinical development of rare diseases, since placebo groups in double-blind randomization trials may not be available due to ethical reasons and low disease prevalence. This article proposed an innovative approach for utilizing natural history data to support rare disease
arxiv   +1 more source

Rare thyroid diseases [PDF]

open access: yesThyroid Research, 2013
In general, rare thyroid diseases can be divided into neoplastic and non-neoplastic. Neoplastic rare thyroid diseases include the following: 1. primary thyroid lymphoma (1-5% all malignant neoplasms of the thyroid; 2:1 000 000 per year); 2. metastases to the thyroid gland (2-3% malignant thyroid neoplasms; 0.5-2.8% in autopsy) from various ...
openaire   +2 more sources

Localization accuracy of 6‐second CBCT for lung IGRT with various breathing patterns

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose The 6‐second cone beam computed tomography (CBCT) acquisition of the Ethos HyperSight (Varian Medical Systems, Inc. Palo Alto, CA, USA) on‐board imaging system offers benefits, but could be too fast to accurately capture an average target position in a free‐breathing lung cancer patient. This study aimed to ascertain whether a 6‐second
Jihye Koo   +5 more
wiley   +1 more source

Mitochondrial DNA disorders in neuromuscular diseases in diverse populations

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao   +34 more
wiley   +1 more source

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