Results 201 to 210 of about 45,763 (247)

Harnessing Vinylogy with Radicals: Photoinduced γ‐Benzylation Reactions of 2‐Silyloxyfurans

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Two radical‐mediated benzylations of 2‐silyloxyfurans, promoted by visible light and suitable photoredox catalysts have been disclosed. A broad scope of γ‐benzyl butenolides was obtained in one step, some of which were used as strategic precursors to bio‐valuable chiral butanolides.
Enrico Marcantonio   +12 more
wiley   +1 more source

CELL TO CELL COMMUNICATION IN GLIOBLASTOMA PROGRESSION: INTRATUMORAL SYNAPSES?

open access: yesIBRO Neuroscience Reports, 2023
María Losada-Pérez   +3 more
doaj  

Optimization of the Isolation Method for Large‐Scale Production of Synthetic Bacterial Vesicles for Cancer Immunotherapy

open access: yesAdvanced Therapeutics, EarlyView.
This study introduces a reliable technique for the large‐scale production of bacterial vesicles that maintain their immune‐modulating potential, enabling industrial manufacturing and clinical applications. Although other cancer immunotherapies are available, this research presents an advanced bacterial vesicle‐based therapeutic option, with scalable ...
Negar Ordouzadeh   +6 more
wiley   +1 more source

Fibronectin Fibers Progressively Lose Their Tension in Invasive Human Breast Carcinoma while Being Tensed in DCIS and Healthy Breast Tissue

open access: yesAdvanced Science, EarlyView.
Extracellular matrix remodeling is crucial in cancer progression. Using a peptide to probe the tension of ECM fibers, it was found that Fibronectin fibers gradually lose tension as human breast carcinoma progresses, while their tension is maintained in ductal carcinoma in situ (DCIS), the non‐invasive precursor of breast cancer. This loss of tension is
Arnaud Miéville   +6 more
wiley   +1 more source

Cutaneous Sarcoidosis of the Scrotum: A Rare Manifestation of Systemic Disease

open access: gold, 2002
Susan S. McLaughlin   +2 more
openalex   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

open access: yesAdvanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song   +9 more
wiley   +1 more source

A Multifunctional Nanodelivery System Modified by Fusion Peptides Acts as Teriparatide Carrier for Noise‐Induced Hearing Loss Therapy

open access: yesAdvanced Science, EarlyView.
The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li   +12 more
wiley   +1 more source

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