Results 81 to 90 of about 89,932 (268)
Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
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Juvenile Huntington Disease With Cerebellar‐Predominant Atrophy Identified by Genome Sequencing
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Juvenile Huntington disease accounts for a small fraction of Huntington disease cases and is driven by the largest trinucleotide repeat expansions. We describe a 6‐year‐old boy with progressive global regression, generalized dystonia, and epilepsy, in whom serial imaging showed striking cerebellar‐predominant atrophy with an initially normal ...
Enrique Gonzalez Saez‐Diez +5 more
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Effect of Deformation Process on Mechanical Properties of Hot-Extruded Mg-Y-Zn-Gd-Zr-Ca Alloy
CrystalsMg–Y–Zn alloys have attracted considerable attention for lightweight structural applications; however, the influence of extrusion temperature on microstructural evolution and the underlying mechanisms governing strength–ductility synergy remains ...
He Guo +7 more
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Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li +17 more
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Influence of Nb mass fraction on properties of conductive Cu alloys
Fenmo yejin jishuThe Cu alloys containing different mass fractions of Nb (0.90%, 0.95%, 1.00%, 1.50%) were prepared by omni-directional planetary ball mill and microwave muffle furnace.
GONG Yanhang +6 more
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Arthritis Care &Research, EarlyView.Objective This research article aims to describe the prevalence, associations, and health‐related quality of life (HRQoL) impact of mucocutaneous features of systemic lupus erythematosus (SLE). Methods Data from the Asia‐Pacific Lupus Collaboration cohort were analyzed (2013–2021).
Amanda M. Saracino +42 more
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Arthritis Care &Research, EarlyView.Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
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Cailiao gongchengThe service performance and operation life of thermal barrier coatings are closely related to the phase composition and structure of the bond coat alloy， which is directly determined by its composition.
CHEN Xuyang +6 more
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Arthritis Care &Research, EarlyView.Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin +14 more
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Scientific ReportsImproving energy efficiency in rare-earth molten salt electrolysis is challenging due to strong process nonlinearity, limited evaluation budgets, and strict operational constraints.
Yu Liu, Jun Peng, Fan Yang, Haitao Guo
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