Results 61 to 70 of about 399,833 (294)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Mining Situation and Geochemistry Characteristics of Three Ion Adsorption Rare-Earth Deposit in Guangdong Province

open access: yesYankuang ceshi, 2014
Guangdong has abundant kinds of rare earth element resources. The resource which could satisfy the industry exploitation is only the ion adsorption type of rare earth ores.
HUANG Hua-gu   +3 more
doaj   +2 more sources

Temperature-induced reversal of magnetic interlayer exchange coupling

open access: yes, 2008
For epitaxial trilayers of the magnetic rare-earth metals Gd and Tb, exchange coupled through a non-magnetic Y spacer layer, element-specific hysteresis loops were recorded by the x-ray magneto-optical Kerr effect at the rare-earth $M_5$ thresholds. This
F. Heigl   +7 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Role of critical spin fluctuations in ultrafast demagnetization of transition-metal rare-earth alloys

open access: yes, 2013
Ultrafast magnetization dynamics induced by femtosecond laser pulses have been measured in ferrimagnetic Co0.8Gd0.2, Co.74Tb.26 and Co.86Tb.14 alloys. Using element sensitivity of X-ray magnetic circular dichroism at the Co L3, Tb M5 and Gd M5 edges we ...
Beaurepaire, E.   +8 more
core   +3 more sources

Garnet–monazite rare earth element relationships in sub-solidus metapelites: a case study from Bhutan [PDF]

open access: yes, 2018
A key aim of modern metamorphic geochronology is to constrain precise and accurate rates and timescales of tectonic processes. One promising approach in amphibolite and granulite-facies rocks links the geochronological information recorded in zoned ...
Argles, Tom W.   +5 more
core   +9 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Rare Earth Element Contents and Occurrence Forms in Weathering Crust Ion Adsorption Rare Earth Ore

open access: yesYankuang ceshi
The weathering crust ion adsorption type rare earth deposit has the characteristics of complete REE types, low radioactivity, high heavy rare earth contents, and easy mining, making it an extremely important type of rare earth deposit.
Xilian XIAO   +5 more
doaj   +1 more source

Effect of Rare Earth Oxide on Electrochemical behaviors of Ni-MH Battery on New Energy Vehicle

open access: yesChemical Engineering Transactions, 2018
Ni-MH Battery used in New Energy Vehicle (NEV) often presents poor electrochemical behaviors under high temperature condition. In view of this gap, this paper explores electrochemical behaviors of such Ni-MH battery that contains rare-earth elements (Y ...
Mengxiong Lu
doaj   +1 more source

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