Results 71 to 80 of about 399,833 (294)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Coal ash resources and potential for rare earth element production in the United States

International Journal of Coal Science & Technology
The renewable energy industry is heavily reliant on rare earth elements, underscoring the need to develop resources and production. The objective of this work was to estimate coal ash resources and potential for extraction of rare earth elements using ...
Robert C. Reedy, Bridget R. Scanlon, Davin A. Bagdonas, James C. Hower, Dennis James, J. Richard Kyle, Kristine Uhlman   +6 more
doaj   +1 more source

Anisotropic rare-earth spin ensemble strongly coupled to a superconducting resonator

, 2012
Interfacing photonic and solid-state qubits within a hybrid quantum architecture offers a promising route towards large scale distributed quantum computing.
Bushev, P. A., Jerger, M., Jung, P., Probst, S., Rotzinger, H., Siegel, M., Ustinov, A. V., Wünsch, S.   +7 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Evaluation on Delineation Methods for Ion-adsorption Type Rare Earth Ore Body

Yankuang ceshi, 2013
Ion-adsorption type rare earth ore is unique and a valuable resource in China. Total rare earth oxides (SREO) and leaching quantities of rare earth oxides (SREO) are important indices of evaluation of the scope and value of rare earth resources.
DENG Mao-chun, WANG Deng-hong, ZENG Zai-lin, ZHANG Yong-zhong, ZHAO Zhi, ZOU Xin-yong, CHEN Bin-feng   +6 more
doaj  

Rare Earth Element Concentrations in Brazilian Benchmark Soils

Revista Brasileira de Ciência do Solo
: Studies regarding background concentrations of rare earth elements (REEs) are scarce and have mainly focused on a limited number of soil types from the northern hemisphere.
Ygor Jacques Agra Bezerra da Silva, Clístenes Williams Araújo do Nascimento, Yuri Jacques Agra Bezerra da Silva, Caroline Miranda Biondi, Cinthia Maria Cordeiro Atanázio Cruz Silva   +4 more
doaj   +1 more source

Effect of rare earth elements substitution in La site for LaMnO3 Manganites [PDF]

, 2012
With a view to understanding the effect of rare earth element (Ce, Pr, Nd, Sm and Gd) substitution for the La site in LaMnO3 (LMO), the samples were prepared via solid-state reaction.
Chen, Soo Kien, Gan, Albert Han Ming, Lim, Kean Pah, Ng, Siau Wei, Shaari, Abdul Halim, Wong, Jen Kuen   +5 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source