Results 101 to 110 of about 8,893 (314)

A gaskinetic model for background flow effects on rarefied jet flow [PDF]

, 2017
© 2017 by the American Institute of Aeronautics and Astronautics, Inc. All rights reserved. We report some work on studying interactions between rarefied background and jet flows by considering two problems.
Cai, Shiying, He, Xin, Cai, Chunpei, Zhang, Kai   +3 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Rarefaction and thermal creep effects in square cross-section microchannels [PDF]

, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Aliabadi, S, Palle, S, 3rd Micro and Nano Flows Conference (MNF2011)   +2 more
core  

A Cross-Regime Coupling Method for Conjugate Heat Transfer in Microscale Systems

Aerospace
In this work, a partitioned coupling algorithm is developed by integrating the improved discrete velocity method (IDVM) with the lattice Boltzmann flux solver (LBFS) to address conjugate heat transfer (CHT) in microscale systems across all flow regimes ...
Yunlong Ge, Yinjie Du, Linchang Han, Liming Yang   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Change in drag, apparent slip and optimum air layer thickness for laminar flow over an idealised superhydrophobic surface [PDF]

, 2013
Analytic results are derived for the apparent slip length, the change in drag and the optimum air layer thickness of laminar channel and pipe flow over an idealised superhydrophobic surface, i.e. a gas layer of constant thickness retained on a wall.
Newton, M.I., Sandham, ND, Busse, A., Newton, MI, McHale, G., McHale, Glen, Sandham, Neil D., Busse, Angela, Newton, Michael, Newton, Michael I., McHale, G, Busse, A, Sandham, N., Sandham, Neil   +13 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Oscillatory rarefied gas flow inside rectangular cavities [PDF]

, 2014
Two-dimensional oscillatory lid-driven cavity flow of a rarefied gas at arbitrary oscillation frequency is investigated using the linearized Boltzmann equation.
Reese, Jason M., Zhang, Yonghao, Wu, Lei, Reese, Jason   +3 more
core   +1 more source

SIMULATION OF RAREFIED GAS FLOW IN A RECTANGULAR ENCLOSURE

Proceeding of Proceedings of the 24th National and 2nd International ISHMT-ASTFE Heat and Mass Transfer Conference (IHMTC-2017), 2018
The present work investigates the effects of rarefaction on gas flow patterns in a lid-driven cavity using the simulation package dsmcFoam, on the OpenFOAM platform. Direct Simulation Monte Carlo (DSMC) method is a simulation technique which caters to the regime in between the computationally intensive molecular dynamics solvers, as well as the often ...
Sumit Chamling Rai, Jayesh Sanwal, K Ram Chandra Murthy   +2 more
openaire   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source