Results 51 to 60 of about 807,261 (265)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Rare books as historical objects: a case study of the Elmer E. Rasmuson Library rare books collection [PDF]

open access: yes, 2016
Thesis (M.S.) University of Alaska Fairbanks, 2015Once upon a time all the books in the Arctic were rare books, incomparable treasures to the men and women who carried them around the world.
Korotkova, Ulyana Aleksandrovna   +1 more
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Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Homologació de rareses ornitològiques a Balears. Informe de 2002 [PDF]

open access: yes
Homologació de rareses ornitològiques a Balears. Informe de 2002. Dotzè informe anual que presenta el Comitè de Rareses Ornitològiques del GOB. S'han homologat 18 registres, corresponents a les següents espècies, moretó cabussó Aythya marila, esmerla ...
López-Jurado, Carlos
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The Yellow-­crowned Night Heron Nyctanassa violacea (Aves: Pelecaniformes: Ardeidae) in the Azores and Madeira Archipelagos: a new species for the Western Palearctic [PDF]

open access: yes, 2014
This paper presents and describes the first confirmed occurrence of the Yellow-crowned Night Heron Nyctanassa violacea in the Azores, which also represents the first record for Europe and the Western Palearctic.
Barcelos, Luís Miguel Duarte   +6 more
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Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Homologació de rareses ornitològiques a Balears. Informe de 2011 [PDF]

open access: yes
Homologació de rareses ornitològiques a Balears. Informe de 2011. 21è informe anual que presenta el comitè de rareses Ornitològiques de Balears. S’han homologat 27 registres, corresponents a les següents espècies, ànnera canyella Tadorna ferruginea ...
García-Febrero, Òscar   +5 more
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Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

The official student newspaper of the University of Alaska Southeast - Juneau [PDF]

open access: yes, 1990
Bishop Kenny shares Middle East experiences -- New classrooms proposed for UAS Campus -- Honors Brass Quintet offers workshop, concerts -- If you Don't Like It; Get Involved and Change It!

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