Results 111 to 120 of about 410,972 (315)
British Journal of Clinical Pharmacology, EarlyView.Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk +5 more
wiley +1 more source
Familial focus of combined course of whooping cough and measles: clinical observation
Детские инфекции (Москва)The incidence of whooping cough is usually higher than the official statistics due to underdiagnosis of the infection, especially in older children.
O. P. Popova +6 more
doaj +1 more source
Perspective: outsourcing jobs overseas: a cause for concern? [PDF]
A rash of media stories has heightened concern about foreign outsourcing of U. S. jobs. But analyses show that many of these reports may have exaggerated the extent and economic impact of jobs moving overseas.Contracting out ...
Jane Sneddon Little
core
British Journal of Clinical Pharmacology, EarlyView.Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti +9 more
wiley +1 more source
EPI Update, May 18, 2010 [PDF]
, 2010 Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...
core
British Journal of Clinical Pharmacology, EarlyView.Aim Elexacaftor/tezacaftor/ivacaftor (ETI) has markedly improved cystic fibrosis (CF) outcomes. However, its long‐term impact on nutrition, metabolism and liver health remains underexplored. We assessed 30‐month changes in pulmonary, nutritional, metabolic and inflammatory markers in people with CF (PwCF) homozygous for F508del.
Nicola Perrotta +5 more
wiley +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Rickettsia sibirica mongolitimonae Infections in Spain and Case Review of the Literature
Emerging Infectious DiseasesRickettsia sibirica mongolitimonae is an emerging cause of tickborne rickettsiosis. Since the bacterium was first documented as a human pathogen in 1996, a total of 69 patients with this infection have been reported in the literature.
Sonia Santibáñez +19 more
doaj +1 more source