Results 61 to 70 of about 410,972 (315)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Clinico-epidemiological and laboratory profiles of scrub typhus in a tertiary care hospital in eastern India: an observational study

MGM Journal of Medical Sciences
Background: Scrub typhus is an acute febrile illness that resembles other common febrile conditions such as leptospirosis, typhoid fever, malaria, and dengue.
Sudeshna Mallik, Boudhayan Bhattacharjee, Swarajdeep Banik, Prantiki Halder, Sonali Das   +4 more
doaj   +1 more source

Essential Updates 2024–2025: Surgical Strategy for Esophageal Cancer Toward a New Paradigm in the Era of Immunotherapy and Personalization

Annals of Gastroenterological Surgery, EarlyView.
This review summarizes key advances from 2024 to 2025 that are reshaping esophageal cancer surgery toward a strategy‐oriented, personalized paradigm through the integration of immunotherapy, population aging, and intelligent technologies. Adjuvant nivolumab after neoadjuvant chemoradiotherapy remains the only perioperative approach with durable benefit,
Shuichiro Oya, Koichi Yagi, Yoshifumi Baba   +2 more
wiley   +1 more source

Leukocytoclastic vasculitis caused by sulfamethoxazole‐trimethoprim

Clinical Case Reports
Key Clinical Message Leukocytoclastic vasculitis is a rare, small‐vessel vasculitis that can be caused by sulfamethoxazole‐trimethoprim. Most presentations involve skin rash but serious systemic involvement is possible.
Parjanya Bhatt, Nadine Montreuil, Ayoola Olayiwola, Tanya Quiroz, Felipe Ruiz, Folusakin Ayoade   +5 more
doaj   +1 more source

Drug-induced anti-Ro positive subacute cutaneous lupus in a man treated with olmesartan [PDF]

, 2019
A 66-year-old man presented to the outpatient dermatology clinic with a chief complaint of a pruritic rash on his upper trunk and proximal upper extremities, which had been present for three weeks.
Farsi, Maheera, Gray, Taylor, Miller, Richard, Ross, Risa, Segars, Kelly   +4 more
core  

Phase I dose-escalation and pharmacokinetic study of dasatinib in patients with advanced solid tumors [PDF]

, 2009
PURPOSE: To determine the maximum tolerated dose, dose-limiting toxicity (DLT), and recommended phase II dose of dasatinib in metastatic solid tumors refractory to standard therapies or for which no effective standard therapy exists.
Agarwal, Shruti, Brunton, Valerie G., Demetri, George D., Evans, T.R. Jeffry, Lo Russo, Patricia, MacPherson, Iain R.J., Morgan, Jeffrey A., Paliwal, Prashni, Voi, Maurizio, Wang, Ding   +9 more
core   +1 more source

Machine Learning‐Augmented Loop‐Mediated Isothermal Amplification‐Enabled Point‐of‐Care for Mpox‐Specific Detection

Advanced Intelligent Systems, EarlyView.
A low‐cost, portable point‐of‐care platform for rapid Mpox detection using loop‐mediated isothermal amplification is reported. The device integrates fluorescence readout and mobile monitoring. A machine‐learning model analyzes temperature data and correlates thermal changes with DNA concentration, enabling sensitive and reliable molecular diagnosis in ...
Nazente Atceken, Ahmed Choukri Abdullah, Olgac Ozarslan, Ziya Yıldız, Savas Tasoglu   +4 more
wiley   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

Hepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou, Yongkun Sun, Wen Zhang, Jiajia Yuan, Zhi Peng, Wei Wang, Jifang Gong, Lin Yang, Yanshuo Cao, Hong Zhao, Chao Chen, Weifeng Wang, Lin Shen, Aiping Zhou   +13 more
wiley   +1 more source

An Atypical Local Vesicular Reaction to the Yellow Fever Vaccine

Vaccines, 2017
Yellow fever vaccine is a live attenuated viral inoculation indicated for patients traveling to endemic areas. The vaccine is generally well tolerated with minimal adverse effects.
Robert H. Wauters, Camellia L. Hernandez, Maureen M. Petersen   +2 more
doaj   +1 more source

Using photovoice to understand community perceptions of firearm risks and protective factors among Asian Americans

American Journal of Community Psychology, EarlyView.
Abstract This study used photovoice methodology to explore Asian Americans' perspectives on the root causes and protective factors of firearm violence in their communities. Photovoice provided a participatory platform for community members to document lived experiences and identify priorities for change.
Tsu‐Yin Wu, Szu‐Hsien Chen, Xining Yang, Ken Resnicow, Hsing‐Fang Hsieh   +4 more
wiley   +1 more source