Results 51 to 60 of about 1,158 (166)

Exploring pathways leading to drug‐resistant epilepsy for patients with cryptogenic new onset refractory status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective Cryptogenic new onset refractory status epilepticus (cNORSE) carries high risks of long‐term disability and post‐NORSE epilepsy, but mechanisms remain unclear. We aimed to assess the predictive value of inflammatory and brain injury biomarkers and determine whether immune disturbances persist in the chronic phase. Methods We enrolled
Aurélie Hanin   +34 more
wiley   +1 more source

STATUS EPILEPTICUS IN A PATIENT WITH RASMUSSEN’S ENCEPHALITIS

open access: yesAlʹmanah Kliničeskoj Mediciny, 2016
We describe clinical case of Rasmussen's encephalitis in a 24-year-old woman that occurred during her hospital stay. Its clinical manifestations included a  clonic movement disorder and partial epilepsy.
A. S. Kotov A.S.   +6 more
doaj   +1 more source

Peri-insular hemispherotomy in paediatric epilepsy [PDF]

open access: yes, 2018
Objects: Outline the indications, investigation, surgical technique, pitfalls, complications and benefits of peri-insular hemispherotomy (PIH) in the surgical treatment of paediatric epilepsy.
Daniel, Roy, Villemure, Jean-Guy
core  

Management of two cases of Rasmussen's Encephalitis at the department of pediatric neurology at the FANN National Hospital in Dakar, Senegal [PDF]

open access: yes, 2021
Rasmussen encephalitis is a rare autoimmune disease first described in the late 50s. It diagnosis requires multidisciplinary participation around the neuropediatrician.
DIOP SENE, Marième Soda   +5 more
core   +1 more source

Serum NfL, GFAP, and p‐tau217 in adults with drug‐resistant epilepsy and intellectual disabilities: Signs of ongoing neural injury

open access: yesEpilepsia, EarlyView.
Abstract Objective Adults with epilepsy and intellectual disabilities (IDs) may be at increased risk of dementia, but clinical evaluation is complex and use of conventional biomarkers is often considered too invasive. We explored abnormality of serum neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and phosphorylated tau‐217 (p ...
Hadassa Kwetsie   +10 more
wiley   +1 more source

Advances of molecular imaging in epilepsy [PDF]

open access: yes, 2016
Positron emission tomography (PET) is a neuroimaging method that offers insights into the molecular functioning of a human brain. It has been widely used to study metabolic and neurotransmitter abnormalities in people with epilepsy.
Galovic, M, Koepp, M
core   +2 more sources

Glymphatic dysfunction couples with cortical excitation–inhibition imbalance in epilepsy: Evidence from Rasmussen encephalitis

open access: yesEpilepsia, EarlyView.
Cong Fu et al. demonstrate that glymphatic system dysfunction is linked to enhanced inhibitory cortical activity using diffusion MRI and EEG. These findings highlight a mechanistic link between perivascular fluid dynamics and neuronal activity, suggesting a role for glymphatic function in maintaining cortical stability in epilepsy.
Cong Fu   +11 more
wiley   +1 more source

Automated diagnosis of encephalitis in pediatric patients using EEG rhythms and slow biphasic complexes [PDF]

open access: yes, 2020
Slow biphasic complexes (SBC) have been identified in the EEG of patients suffering for inflammatory brain diseases. Their amplitude, location and frequency of appearance were found to correlate with the severity of encephalitis. Other characteristics of
Capizzi G., Mesin L., Valerio M.
core   +1 more source

Epilepsy syndromes classification

open access: yesEpilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell   +4 more
wiley   +1 more source

Global disparities in the recognition, diagnosis, and management of seizures or epilepsy of autoimmune etiology

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Despite advancements in “autoimmune epilepsy,” more accurately referred to herein as seizures or epilepsy of autoimmune etiology, significant variability exists in its recognition, diagnosis, and management internationally. This study assessed clinicians' understanding, access to diagnostic tools, and treatment practices across ...
Emily Guarasci   +3 more
wiley   +1 more source

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