Results 61 to 70 of about 1,158 (166)

The changing landscape in epilepsy imaging: Unmasking subtle and unique entities

Diagnostic and Interventional Radiology, 2022
Dramatic changes have occurred recently in the field of epilepsy, including a fundamental shift in the etiology of epileptogenic substrates found at surgery. Hippocampal sclerosis is no longer the most common etiology found at epilepsy surgery and this
Mehmet E. Adin, David Durand, William B Zucconi, Anita J Huttner, Dennis D Spencer, Richard A Bronen   +5 more
doaj   +1 more source

Targeting Inflammatory Mediators in Epilepsy: A Systematic Review of Its Molecular Basis and Clinical Applications [PDF]

, 2022
Introduction: Recent studies prompted the identification of neuroinflammation as a potential target for the treatment of epilepsy, particularly drug-resistant epilepsy, and refractory status epilepticus.
Bonuccelli A., Consolini R., Costagliola G., Depietri G., Foiadelli T., Marseglia G. L., Michev A., Orsini A., Peroni D., Riva A., Savasta S., Striano P.   +11 more
core   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Epidemiology of progressive intellectual and neurological deterioration in UK children

Developmental Medicine &Child Neurology, Volume 68, Issue 3, Page 418-428, March 2026.
This study of PIND in UK children was carried out via the British Paediatric Surveillance Unit from 1997 to 2024. It identified six cases of vCJD. 2367 children had other diagnoses explain their deterioration. There were 259 other diseases in the diagnosed group.
Christopher M. Verity, Polly J. Maunder, Anne Marie Winstone, Suvankar Pal   +3 more
wiley   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, Volume 13, Issue 2, Page 296-309, February 2026.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Rasmussen's encephalitis. Clinical case of surgical treatment

Acta Biomedica Scientifica, 2013
The article presents literary data on the clinical course, diagnostics and treatment of Rasmussen's encephalitis in children. Epileptic attacks at Rasmussen's encephalitis are resistant to the anti-convulsion therapy and.
S. N. Larionov, V. A. Sorokovikov, Yu. A. Alexandrov, E. B. Khaykina, E. K. Pulyaevskaya   +4 more
doaj  

Young woman with a four-year history of epilepsy and progressive focal cortical atrophy — What is the diagnosis?

Epilepsy and Behavior Case Reports, 2014
The pathogenesis of disease progression in drug-refractory epilepsy is poorly understood. We report the case of a young woman with a four-year history of epilepsy that progressed rapidly as evidenced by the development of progressive focal cortical ...
S. Pati, M.I. Cobos-Sillero, B. Buchbinder, E. Eskandar, A.J. Cole   +4 more
doaj   +1 more source

Predictors of etiology and drug resistance in children with new‐onset focal seizures

Epilepsia Open, Volume 11, Issue 1, Page 123-135, February 2026.
Abstract Objective To examine the clinical features of new‐onset focal seizures in children and investigate clinical associations and predictors of underlying etiology and drug resistance. Methods Data were gathered from The Children's Hospital at Westmead admissions for patients aged 1 month to 18 years who presented with new‐onset focal seizures ...
Byoung Chan Lee, Russell C. Dale, Elizabeth H. Barnes, Shekeeb S. Mohammad, Sachin Gupta, Chong Wong, Deepak Gill, Kavitha Kothur   +7 more
wiley   +1 more source

Understanding Childhood Neuroimmune Diseases of the Central Nervous System [PDF]

, 2019
Immune-mediated diseases of the central nervous system (CNS) in childhood are a heterogeneous group of rare conditions sharing the inflammatory involvement of the CNS.
Farello G, Matricardi S, Savasta S, Verrotti A   +3 more
core   +4 more sources

HCMV infection and IFITM3 rs12252 are associated with Rasmussen's encephalitis disease progression

Annals of Clinical and Translational Neurology, 2021
Objective Rasmussen’s encephalitis (RE) is a rare and severe progressive epileptic syndrome with unknown etiology. Infection by viruses such as human cytomegalovirus (HCMV) has been hypothesized to be a potential trigger for RE.
Yi‐Song Wang, Qiao‐Li Luo, Yu‐Guang Guan, Dong‐Ying Fan, Guo‐Ming Luan, An Jing   +5 more
doaj   +1 more source