Results 21 to 30 of about 122 (87)

CD8+ T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing

Nature Communications, 2016
Rasmussen Encephalitis is a rare neurological disease accompanied by inflammation and T cell infiltration in the brain. Here the authors show that the severity of this disease correlates with clonal CD8 T cell expansion.
Tilman Schneider-Hohendorf, Hema Mohan, Christian G. Bien, Johanna Breuer, Albert Becker, Dennis Görlich, Tanja Kuhlmann, Guido Widman, Sebastian Herich, Christiane Elpers, Nico Melzer, Klaus Dornmair, Gerhard Kurlemann, Heinz Wiendl, Nicholas Schwab   +14 more
doaj   +1 more source

Rasmussen Encephalitis with Delayed Seizure Onset

Pediatric Neurology Briefs, 2004
Two children, ages 6 and 7 years, with progressive hemiparesis and radiological and histopathological confirmation of Rasmussen encephalitis (RE) had no seizures or epileptic EEG activity until 6 to 7 months after onset of symptoms, in a report from ...
J Gordon Millichap
doaj   +1 more source

An immunotherapy effect analysis in Rasmussen encephalitis

BMC Neurology, 2020
Background Immune-mediated mechanisms substantially contribute to the Rasmussen encephalitis (RE) pathology, but for unknown reasons, immunotherapy is generally ineffective in patients who have already developed intractable epilepsy; overall laboratory ...
Zuzana Liba, Martina Vaskova, Josef Zamecnik, Jana Kayserova, Hana Nohejlova, Matyas Ebel, Jan Sanda, Gonzalo Alonso Ramos-Rivera, Klara Brozova, Petr Liby, Michal Tichy, Pavel Krsek   +11 more
doaj   +1 more source

Diagnostic misdirection in posterior-onset Rasmussen's encephalitis: A case report

Radiology Case Reports
Rasmussen's encephalitis (RE) is a rare, chronic, and progressive inflammatory brain disorder, characterized by drug-resistant seizures, cognitive decline, and unihemispheric atrophy. Focal neurological deficits and focal motor seizures are typically the
Rihab Ben Dhia, MD, Yasmine Saad, MD, Narjes Gouta, MD, Mariem Mhiri, MD, Mahbouba Frih-Ayed, PhD   +4 more
doaj   +1 more source

Postoperative outcomes and predictors of functional sequelae following hemispheric surgery in Rasmussen's encephalitis: A retrospective cohort study from the global pediatric epilepsy surgery registry

Epileptic Disorders, EarlyView.
Abstract Objective Rasmussen's encephalitis (RE) is a rare and progressive, immune‐mediated epileptic encephalopathy characterized by drug‐resistant seizures and neurological decline. While hemispheric disconnection (HD) is the gold standard treatment for effective seizure control, this procedure carries significant risk of permanent neurological ...
Krish Nair, Nicholas Benjamin, Emily Harford, Levi Shelton, Ariel Heller, Katherine Cobb‐Pitstick, Luis Fernandez, Ross Carson, Monika Jones, William Welch, Taylor J. Abel, Ruba Al‐Ramadhani   +11 more
wiley   +1 more source

Pragmatic screening for autoimmune‐associated epilepsy in drug‐resistant epilepsy of unknown etiology in resource‐limited settings: A hypothesis‐generating study

Epileptic Disorders, EarlyView.
Abstract Objective To evaluate the feasibility of investigating autoimmune etiology in adults with drug‐resistant epilepsy (DRE) of unknown origin in resource‐limited settings and to develop a pragmatic, hypothesis‐generating screening approach to guide autoantibody testing. Methods A prospective observational study including adults with DRE of unknown
Tomásia O. de H. M. Frezatti, Ricardo L. Saute, Veriano Alexandre Júnior, Frederico N. Nakano, Marina T. R. P. Dalio, Tonicarlo R. Velasco, João P. Leite, Antônio Carlos dos Santos, Vanessa D. Marques, Américo C. Sakamoto   +9 more
wiley   +1 more source

Clinical and EEG characteristics of Rasmussen encephalitis in different age groups

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To summarize the clinical and EEG features of patients with different ages of Rasmussen encephalitis to evaluate the efficacy of different surgical methods.
Zhao⁃fen YAN, Jing WANG, Guo⁃ming LUAN, Jian ZHOU, Yu⁃guang GUANG, Feng ZHAI, Meng⁃yang WANG   +6 more
doaj  

Pathology of surgically remediable epilepsy: How to evaluate

Indian Journal of Pathology and Microbiology, 2022
Epilepsy surgery is a well-established treatment modality in selected cases of medically refractory epilepsy. Advances in neuroimaging technology has greatly facilitated detection of lesions that are surgically amenable. Hippocampal sclerosis is the most
Rajalakshmi Poyuran
doaj   +1 more source

Epilepsy syndromes classification

Epilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell, Nicola Specchio, Rima Nabbout, Phillip L. Pearl, Kate Riney   +4 more
wiley   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source