Results 51 to 60 of about 84,070 (218)

Clinic manifestations in granulomatosis with polyangiitis [PDF]

open access: yes, 2016
Granulomatosis with polyangiitis (GPA), formerly Wegener's granulomatosis (WG), is an uncommon immunologically mediated systemic small-vessel vasculitis that is pathologically characterised by an inflammatory reaction pattern (necrosis, granulomatous ...
De Vincentiis, Marco   +7 more
core   +1 more source

Serum NfL, GFAP, and p‐tau217 in adults with drug‐resistant epilepsy and intellectual disabilities: Signs of ongoing neural injury

open access: yesEpilepsia, EarlyView.
Abstract Objective Adults with epilepsy and intellectual disabilities (IDs) may be at increased risk of dementia, but clinical evaluation is complex and use of conventional biomarkers is often considered too invasive. We explored abnormality of serum neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and phosphorylated tau‐217 (p ...
Hadassa Kwetsie   +10 more
wiley   +1 more source

Celiac disease [PDF]

open access: yes, 2006
Celiac disease is a chronic intestinal disease caused by intolerance to gluten. It is characterized by immune-mediated enteropathy, associated with maldigestion and malabsorption of most nutrients and vitamins.
Holtmeier, Wolfgang   +1 more
core   +2 more sources

Epilepsy syndromes classification

open access: yesEpilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell   +4 more
wiley   +1 more source

Characterization of designed, synthetically accessible bryostatin analog HIV latency reversing agents. [PDF]

open access: yes, 2018
HIV latency in resting CD4+ T cell represents a key barrier preventing cure of the infection with antiretroviral drugs alone. Latency reversing agents (LRAs) can activate HIV expression in latently infected cells, potentially leading to their elimination
DeChristopher, Brian A   +11 more
core   +1 more source

Global disparities in the recognition, diagnosis, and management of seizures or epilepsy of autoimmune etiology

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Despite advancements in “autoimmune epilepsy,” more accurately referred to herein as seizures or epilepsy of autoimmune etiology, significant variability exists in its recognition, diagnosis, and management internationally. This study assessed clinicians' understanding, access to diagnostic tools, and treatment practices across ...
Emily Guarasci   +3 more
wiley   +1 more source

Nothing in excess - lessons learned from the expression of high-mobility group proteins type A in non-cancer and cancer cells [PDF]

open access: yes, 2011
High-mobility group A (HMGA) proteins are major transcription regulators which are abundantly and ubiquitously expressed in undifferentiated cells but present at a low level in somatic cells of adult organisms.
Petkova, Rumena   +2 more
core   +3 more sources

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

open access: yesIbrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen   +10 more
wiley   +1 more source

Different behaviour of the N-terminal and C-terminal fragment of proatrial natriuretic factor in plasma of healthy subjects as well as of patients with cirrhosis [PDF]

open access: yes, 1990
N-terminal (atrial natriuretic factor (ANF) 1-98) and C-terminal (ANF 99-126) fragments of proatrial natriuretic factor (NTA and CTA, respectively) were determined in plasma of healthy subjects adopting different postures and in patients with cirrhosis ...
Arendt, Rainer M.   +5 more
core   +1 more source

Maternal influenza vaccination during pregnancy and risk of autism spectrum disorder in the offspring

open access: yesJCPP Advances, EarlyView.
Abstract Background Vaccination has been proposed as a potential risk factor for autism spectrum disorder (ASD), contributing to public hesitancy and mistrust toward immunization. Influenza vaccination during pregnancy is considered safe and effective in preventing serious maternal complications and adverse birth outcomes associated with influenza ...
Shahar Neeman   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy