Results 81 to 90 of about 4,851 (264)

Absence seizures: Update on signaling mechanisms and networks

open access: yesEpilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Evaluation of Sensitivity and Calibration of the Chaboche Kinematic Hardening Model Parameters for Numerical Ratcheting Simulation

open access: yesApplied Sciences, 2019
Ratcheting failure of materials and structures subjected to low cycle fatigue in the presence of significant mean stress is of great interest to researchers.
Navid Moslemi   +4 more
doaj   +1 more source

Dynamic coronal plane knee alignment: Femoral anatomy determines kinematic curve morphology, tibial anatomy determines curve position

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose A single hip–knee–ankle angle (HKA) angle does not reflect the biomechanics of native, arthritic or prosthetic knees. Since HKA varies throughout flexion, dynamic coronal alignment is best represented by a kinematic curve plotting HKA against the range of motion.
Petros Ismailidis   +3 more
wiley   +1 more source

RATCHETING OF STAINLESS STEEL 304 UNDER MULTIAXIAL NONPROPORTIONAL LOADING [PDF]

open access: yes, 2020
Ratcheting tests are conducted on stainless steel 304 under uniaxial, torsional, and combined axial-torsional loading. The ratcheting strain is predicted based on the constitutive theory that incorporates a modified Ohno-Wang kinematic hardening rule and
Kwang S Kim   +3 more
core  

Laparoscopic Methylene Blue Photodynamic Therapy for Intraabdominal Infection: A Preclinical Feasibility Study in a Rabbit Model of Perforated Appendicitis

open access: yesLasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives Perforated appendicitis commonly results in intra‐abdominal infection requiring prolonged antibiotic therapy. Intraoperative antimicrobial adjuncts are limited, and photodynamic therapy (PDT) may provide a targeted, resistance‐independent approach.
Timothy M. Baran   +7 more
wiley   +1 more source

Elastic Stress Ratcheting Assessment Considering Secondary Stress Due to Structural Discontinuity Effect

open access: yesApplied Sciences
The partial secondary stress (hereinafter referred to as secondary mechanical membrane stress QL) generated by structural discontinuity effects is not considered by the current codes and standards and will lead to conservatism in stress analysis results.
Yuping Su, Jun Shen, Hongyan Feng
doaj   +1 more source

Myosin's mechanical ratchet [PDF]

open access: yesProceedings of the National Academy of Sciences, 2006
Myosin molecular motors bind to and exert force upon actin filaments. Between 24 (1) and 37 (2) myosin subfamilies are currently recognized (3), the myriad members of which are specialized for tasks ranging from muscle contraction through to mechano-sensation and signaling, cell polarization, the sliding and tensioning of cytoskeletal elements ...
openaire   +2 more sources

Ratchet nanofiltration of DNA [PDF]

open access: yesLab on a Chip, 2013
The DNA nanofilter is a microfabricated electrophoretic separation device consisting of a periodic array of thin slits (circa 60 nm) separated by deeper wells (circa 320 nm). We demonstrate that this device can act as a tuneable, clog-free filter when operating in a low frequency, asymmetric field inversion mode.
Joel D P, Thomas   +4 more
openaire   +2 more sources

On the Assembly of Actin Polymerization‐Powered Motors

open access: yesMacromolecular Rapid Communications, EarlyView.
Actin polymerization‐powered motors have the highest speed when the actin recruiting‐polymerizing proteins are immobilized in polymer brushes on their surface. These motors orbit around larger tracer particles at pH above the isoelectric point of ActA but dock onto the tracer particles’ surface at lower pH. ABSTRACT Nano‐ and micromotors are a class of
Miguel A. Ramos Docampo   +2 more
wiley   +1 more source

Finite Element Implementation of a Temperature-Dependent Cyclic Plastic Model for SA508-3 Steel

open access: yesMetals, 2018
A new temperature-dependent cyclic plastic model, combining the nonlinear cyclic softening and kinematic hardening rules is established for a nuclear material of SA508-3 steel.
Jun Tian   +4 more
doaj   +1 more source

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