Results 181 to 190 of about 4,998,226 (295)

Suboptimal heart rate control despite beta-blocker use in coronary artery disease: evidence from the Fasa PERSIAN cohort. [PDF]

BMC Cardiovasc Disord
Yazdanpanah MH, Bazmi S, Fakhraei B, Bahramali E, Kazemi M, Zarenezhad E, Jaafari N, Rostaei S, Farjam M.   +8 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Heart rate control with adrenergic blockade: Clinical outcomes in cardiovascular medicine

, 2010
David Feldman1, Terry S Elton2, Doron M Menachemi3, Randy K Wexler41Heart Failure/Transplant and VAD Programs, Minneapolis Heart Institute, Minneapolis, Minnesota, USA; 2Division of Pharmacology, College of Pharmacology, The Ohio State University ...
David Feldman, et al, Terry S Elton, Doron M Menachemi   +3 more
core  

Long-term Outcomes of Atrioventricular Node Ablation and Pacemaker Therapy for Rate Control in Atrial Fibrillation: Insights from a 10-year Nationwide Analysis. [PDF]

Arrhythm Electrophysiol Rev
Caroline Kõre A, Serg M, Ööbik T, Kals M, Paju R, Kolk R, Roose I, Hanni K, Voitk J, Eha J, Kampus P.   +10 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Heart rate monitoring and control in altered gravity conditions

, 2007
Meriggi P, Rizzo F, Heart rate monitoring and control in altered gravity conditions. Di Rienzo M, Merati G, Castiglioni P, Parati G, Faini A   +6 more
core  

Catheter ablation vs rate control in atrial fibrillation with left ventricular systolic dysfunction and fibrosis: the CAMERA-MRI II trial. [PDF]

Eur Heart J
Segan L, Kistler PM, Nanayakkara S, Taylor A, Kaye DM, Hare JL, Costello B, Patel H, Chieng D, Crowley R, William J, Sugumar H, Cho K, Voskoboinik A, Ling LH, Nderitu Z, Azzopardi S, Curtin A, Ahluwalia N, Finlay M, Schilling R, Win KZ, Kalla M, Mariani J, Kumar S, Premaratne M, Parameswaran R, Amerena J, Morton JB, McLellan AJ, Lee G, Theuerle J, Joseph S, Wong M, Kalman JM, Prabhu S.   +35 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Lost Rate Control and Tachycardia-Induced Cardiomyopathy as a Result of an Interaction Between Enzalutamide and Diltiazem. [PDF]

JACC Case Rep
de Boer A, Koshman S, Gyenes G.
europepmc   +1 more source