Results 231 to 240 of about 9,390,253 (340)

A Streamlined 4-item Wolf Motor Function Test for Efficient Assessment of Upper Extremity Motor Function in Chronic Stroke Survivors. [PDF]

Neurorehabil Neural Repair
Kim B, Schweighofer N, Wolf SL, Winstein C.   +3 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Albumin Levels Are Predictive of Cachexia-Induced Time-Dependent Clearance of Therapeutic Antibodies: A Physiologically Based Pharmacokinetic Model of Durvalumab. [PDF]

CPT Pharmacometrics Syst Pharmacol
Proctor JR, Wong H.
europepmc   +1 more source

Approximation Rates for Scattered-data Interpolation of Sobolev Functions via Gaussians and Allied Functions

, 2013
Keaton Hamm
openalex   +1 more source

Convergence rate of $\ell^p$-relaxation on a graph to a $p$-harmonic function with given boundary values [PDF]

Chee Kwan Gan, Yuval Peres, Junchi Zuo
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Application of the Richards function to serum antibody titration. [PDF]

Front Immunol
Kovács Á, Papp K, Prechl J, Pfeil T.
europepmc   +1 more source

Optimization of material removal rate in milling of thin-walled structures using penalty cost function

, 2019
Kasper Ringgaard, Yaser Mohammadi, Christian Haastrup Merrild, Ole Balling, Keivan Ahmadi   +4 more
openalex   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The High-Resolution Rate-Distortion Function under the Structural Similarity Index

EURASIP Journal on Advances in Signal Processing, 2011
Jan Østergaard, Milan S. Derpich, Sumohana S. Channappayya   +2 more
doaj   +1 more source