Results 101 to 110 of about 1,545,364 (282)

Feedback Communication Systems with Limitations on Incremental Redundancy [PDF]

open access: yes, 2013
This paper explores feedback systems using incremental redundancy (IR) with noiseless transmitter confirmation (NTC). For IR-NTC systems based on {\em finite-length} codes (with blocklength $N$) and decoding attempts only at {\em certain specified ...
Chen, Tsung-Yi   +3 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A study of (σ, μ)-Stancu-Schurer as a new generalization and approximations

open access: yesJournal of Inequalities and Applications
The goal of this manuscript is to introduce a new sequence as (σ, μ)-Stancu-Schurer operators. Further, some estimates are calculated as test functions and central moments.
Nadeem Rao   +2 more
doaj   +1 more source

Economy of Effort or Maximum Rate of Information? Exploring Basic Principles of Articulatory Dynamics

open access: yesFrontiers in Psychology, 2019
Economy of effort, a popular notion in contemporary speech research, predicts that dynamic extremes such as the maximum speed of articulatory movement are avoided as much as possible and that approaching the dynamic extremes is necessary only when there ...
Yi Xu, Santitham Prom-on
doaj   +1 more source

Secular non-secular master equation

open access: yes, 2017
Redfield non-secular master equation governing relaxation of a spin in weak interaction with a thermal bath is studied. Using the fact that the relaxation follows the exponential law, we prove that in most cases the semi-secular approximation is ...
Chibotaru, Liviu F., Ho, Le Tuan Anh
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Accelerated method of finding for the minimum of arbitrary Lipschitz convex function

open access: yes, 2019
The goal of the paper is development of an optimization method with the superlinear convergence rate for an arbitrary convex function. For optimization an approximation is used that is similar to the Steklov integral averaging.
Prudnikov, I. M.
core  

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