Results 131 to 140 of about 1,545,364 (282)

Approximation of Mellin convolution-type nonlinear integral operators in variable bounded variation spaces

open access: yesJournal of Inequalities and Applications
In this paper, we investigate approximation properties using a family of Mellin convolution-type integral operators within the framework of variable bounded variation spaces with the help of summability methods.
Hemen Dutta, Manash Pratim Dutta
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Corrigendum to “Rate of Approximation for Modified Lupaş-Jain-Beta Operators”

open access: yesJournal of Function Spaces, 2021
M. Qasim   +4 more
doaj   +1 more source

A note on Lototsky–Bernstein bases

open access: yesJournal of Inequalities and Applications
In this note, we study some approximation properties on a class of special Lototsky–Bernstein bases. We focus on approximation of | x | $|x|$ on [ − 1 , 1 ] $[-1,1]$ by an approximation process generated from fixed points on Lototsky–Bernstein bases. Our
Xiao-Wei Xu   +4 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The Validity of Long Wavelength Approximation in the Evaluation of Two-Photon Decay Rate

open access: yesAtoms
This paper investigates the validity of the long wavelength approximation in the calculation of two-photon decay of 2s1/2 level in hydrogen-like ions with nuclear charge Z=1−100 based on time-dependent second-order perturbation theory and angular ...
George-Tony Constantin, Cristian Iorga
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Approximation of fractional derivatives by Brass-Stancu operators

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica
In this paper, we study uniform approximation of fractional derivatives in Caputo sense by Brass-Stancu operators. For the rate of approximation, we give some estimates in terms of the modulus of continuity.
Başcanbaz-Tunca Gülen   +3 more
doaj   +1 more source

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