Results 61 to 70 of about 252,763 (271)

A uniform estimate for the rate of convergence in the multidimensional central limit theorem for homogeneous Markov chains

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1996
In this paper a uniform estimate is obtained for the remainder term in the central limit theorem (CLT) for a sequence of random vectors forming a homogeneous Markov chain with arbitrary set of states.
M. Gharib
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Calculating the Weighted Moore–Penrose Inverse by a High Order Iteration Scheme

open access: yesMathematics, 2019
The goal of this research is to extend and investigate an improved approach for calculating the weighted Moore−Penrose (WMP) inverses of singular or rectangular matrices. The scheme is constructed based on a hyperpower method of order ten.
Haifa Bin Jebreen
doaj   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

On the Bounds for a Two-Dimensional Birth-Death Process with Catastrophes

open access: yesMathematics, 2018
The model of a two-dimensional birth-death process with possible catastrophes is studied. The upper bounds on the rate of convergence in some weighted norms and the corresponding perturbation bounds are obtained.
Anna Sinitcina   +9 more
doaj   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Bounds on the rate of convergence for one class of inhomogeneous Markovian queueing models with possible batch arrivals and services

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2018
In this paper we present a method for the computation of convergence bounds for four classes of multiserver queueing systems, described by inhomogeneous Markov chains.
Zeifman Alexander   +5 more
doaj   +1 more source

On the rate of convergence for a class of Markovian queues with group services

open access: yesDiscrete and Continuous Models and Applied Computational Science, 2020
There are many queuing systems that accept single arrivals, accumulate them and service only as a group. Examples of such systems exist in various areas of human life, from traffic of transport to processing requests on a computer network. Therefore, our
Anastasia L. Kryukova
doaj   +1 more source

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