Results 101 to 110 of about 915,295 (349)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Optimal bit selection for large-diameter wellbore drilling in an ultra-deep well

Petroleum Exploration and Development
To optimize the bit selection for large-diameter wellbore in the upper section of an ultra-deep well S-1, a full-well dynamic model integrating drill string vibration and bit rock-breaking was established and then verified using measured vibration data ...
Lili CHEN, Wenzhe LI, Jianhua GUO, Ke LI, Zhixiang CAI, Jie WU, Weining XU, Xiaohua ZHU   +7 more
doaj   +1 more source

Determination of the Rate of Penetration by Robust Machine Learning Algorithms Based on Drilling Parameters. [PDF]

ACS Omega, 2023
Alavi Nezhad Khalil Abad SV, Hazbeh O, Rajabi M, Tabasi S, Lajmorak S, Ghorbani H, Radwan AE, Mudabbir M.   +7 more
europepmc   +1 more source

Foreign bank penetration, resource allocation and economic growth: evidence from emerging economies [PDF]

This paper examines the implications of foreign bank penetration on economic growth from the perspective of resource allocation in host countries. We use aggregate banking data, constructed from bank-level balance sheets and income statement information ...
Jeon, Bang Nam, Luca, Alina, Wu, Ji
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

ACCURATE PREDICTION OF DRILL BIT PENETRATION RATE IN ROCK USING SUPERVISED MACHINE LEARNING TECHNIQUES BASE ON LABORATORY TEST DATA

Rudarsko-geološko-naftni Zbornik
Knowing the rate of penetration of a drill bit in rocks is among the most important parameters in their behaviour measurement. However, the direct measurement of ROP in rocks is a high-cost and time-intensive process.
Shahrokh Khosravimanesh, Akbar Esmaeilzadeh, Masoud Akhyani, Reza Mikaeil, Mojtaba Mokhtarian Asl   +4 more
doaj   +1 more source

A Study on Factors Affecting Airborne LiDAR Penetration

Terrestrial, Atmospheric and Oceanic Sciences, 2015
This study uses data from different periods, areas and parameters of airborne LiDAR (light detection and ranging) surveys to understand the factors that influence airborne LiDAR penetration rate.
Wei-Chen Hsu, Peter Tian-Yuan Shih, Hung-Cheng Chang, and Jin-King Liu   +3 more
doaj   +1 more source

Real-time rate of penetration prediction for motorized bottom hole assembly using machine learning methods. [PDF]

Sci Rep, 2023
Shokry A, Elkatatny S, Abdulraheem A.
europepmc   +1 more source

Preliminary study of gaseous nitrogen-liquid oxygen mixing and self cleaning [PDF]

The penetration of gaseous nitrogen into liquid oxygen at a pressure of 150 psi was determined by monitoring the composition of the evaporating liquid in a nitrogen analyzer.
Zuckerwar, A. J.
core   +1 more source