Results 101 to 110 of about 922,670 (302)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Determination of the Rate of Penetration by Robust Machine Learning Algorithms Based on Drilling Parameters. [PDF]

open access: yesACS Omega, 2023
Alavi Nezhad Khalil Abad SV   +7 more
europepmc   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

ACCURATE PREDICTION OF DRILL BIT PENETRATION RATE IN ROCK USING SUPERVISED MACHINE LEARNING TECHNIQUES BASE ON LABORATORY TEST DATA

open access: yesRudarsko-geološko-naftni Zbornik
Knowing the rate of penetration of a drill bit in rocks is among the most important parameters in their behaviour measurement. However, the direct measurement of ROP in rocks is a high-cost and time-intensive process.
Shahrokh Khosravimanesh   +4 more
doaj   +1 more source

A Study on Factors Affecting Airborne LiDAR Penetration

open access: yesTerrestrial, Atmospheric and Oceanic Sciences, 2015
This study uses data from different periods, areas and parameters of airborne LiDAR (light detection and ranging) surveys to understand the factors that influence airborne LiDAR penetration rate.
Wei-Chen Hsu   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Regression Models and Fuzzy Logic Prediction of TBM Penetration Rate

open access: yesOpen Engineering, 2017
This paper presents statistical analyses of rock engineering properties and the measured penetration rate of tunnel boring machine (TBM) based on the data of an actual project.
Minh Vu Trieu   +3 more
doaj   +1 more source

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