Results 111 to 120 of about 21,832,942 (335)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
On the Achievable Rate Region of the K-Receiver Broadcast Channels via Exhaustive Message Splitting. [PDF]
Entropy (Basel), 2021 Tang R, Xie S, Wu Y.
europepmc +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Omicron and S-gene target failure cases in the highest COVID-19 case rate region in Canada-December 2021. [PDF]
J Med Virol, 2022 Li T, Maier A, Carter M, Guan TH.
europepmc +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Clinical Characteristics and Risk Factors for Severe Disease of Coronavirus Disease 2019 in a Low Case Fatality Rate Region in Korea. [PDF]
Infect Chemother, 2021 Kim M, Yoo JR, Heo ST, Lee HR, Oh H.
europepmc +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Regional Intelligence and Suicide Rate in Germany, Revisited
Psychological Reports, 2013 Across the 10 westerly and 6 easterly states of Germany, better-than-average school-end grades, taken as a proxy for intelligence, corresponded to higher regional suicide rates. This finding adds to similar evidence from other countries (Austria, Belarus, British Isles, Denmark, Netherlands, and USA), suggestive of positive ecologic (group-level ...
openaire +5 more sources
Comparing Trends in Cancer Rates Across Overlapping Regions
Biometrics, 2008 Summary Monitoring and comparing trends in cancer rates across geographic regions or over different time periods have been major tasks of the National Cancer Institute's (NCI) Surveillance, Epidemiology, and End Results (SEER) Program as it profiles healthcare quality as well as decides healthcare resource allocations within a spatial–temporal ...
Li, Yi, Tiwari, Ram C.
openaire +4 more sources